Results 111 to 120 of about 4,312,287 (298)

Bioenergy Strategy 2020-2027

open access: yes, 2020
This strategy is founded on intelligence from global and regional trends in bioenergy production and consumption and an understanding of the local bioenergy industry status.

core  

National E-Waste Management Strategy 2019-2024 [PDF]

open access: yes, 2019
The National E-waste Management Strategy is a five-year plan covering the period 2019/20 to 2023/24. The E-waste Strategy has five thematic areas aimed at resource mobilization for proper E-waste management, raising awareness, strengthening Kenya’s E ...

core  

Effects of strategic leadership, organizational innovativeness and information technology capability on effective strategy implementation [PDF]

open access: yes, 2016
The paper examined the role of strategic leadership, organizational innovativeness, information technology capability on strategy implementation in tertiary institutions situated at Kaduna state, Nigeria.
Palladan, Ahmad Aliyu   +2 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Well-being and organizational performance: An organizational-level test of the happy-productive worker hypothesis [PDF]

open access: yes, 2009
It is often assumed that happy workers are also productive workers. Although this reasoning has frequently been supported at the individual level, it is still unclear what these findings imply for organizational performance. Controlling for relevant work
Work and Organizational Psychology: Occupational Health Psychology   +3 more
core   +1 more source

STRATEGIES AND STRUCTURES OF POLISH SMES

open access: yesStudia Universitatis Babeş-Bolyai Negotia, 2016
The topic of strategy-structure relation has already been widely discussed in the literature but the research so far concentrated mainly on large enterprises in developed countries while not much research has been done on a sample of small and medium ...
Wioletta MIERZEJEWSKA
doaj   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

The Organizational Fitness Navigator: Creating and Measuring Organizational Fitness for Fast-Paced Transformation [PDF]

open access: yes
In the fast-changing environment of today dynamic capabilities to manage organizational transformation are regarded as crucial for business survival and improved performance.
Voelpel, Sven C.   +2 more
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