Results 131 to 140 of about 1,157,683 (306)

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

IT in construction: aligning IT and business strategies [PDF]

, 2002
The extent to which information technology (IT) infrastructures and strategies are aligned with business processes and strategies varies widely along firms.
Greenwood, D, Kolkman, S., Laan, A., Laan, Albertus, Leuven, A., Voordijk, Johannes T.   +5 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Organizational Strategy and Corporate Social Responsibility: The Mediating Effect of Triple Bottom Line. [PDF]

Int J Environ Res Public Health, 2019
Masud MAK, Rashid MHU, Khan T, Bae SM, Kim JD.   +4 more
europepmc   +1 more source

Sustainable management: a strategic challenge for a global minerals and metals industry

, 2010
This paper refers to the concept of sustainable management as the management approach which efficiently integrates economic, environmental and social issues into the operations of the minerals and metals industries, with the aim of creating long-term ...
Botin Gonzalez, Jose Antonio, Palacios, Miguel de   +1 more
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

As redes sociais como instrumento estratégico para a inteligência competitiva

Transinformação
O mapeamento das redes sociais permite a visualização das ligações entre atores no ambiente organizacional, constituindo-se, assim, importante recurso para o compartilhamento da informação e do conhecimento.
Adriana Rosecler Alcará, Elaine Cristina Liviero Tanzawa, Ivone Guerreiro Di Chiara, Maria Inês Tomaél, Plínio Pinto de Mendonça Uchoa Junior, Valéria Cristina Heckler, Jorge Luis Rodrigues, Sulamita da Silva Valente   +7 more
doaj  

Towards a Model of Designing an Organizational Structure in a Knowledge Based Society [PDF]

The role of the manager in the knowledge society is to lead, in a productive and cost effective manner, a system that is at the crossroads of three worlds: the environment, the human and the organization. To ensure the continuity of the organization, the
Eric Jolivet, Mihai Vărzaru
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Strategy as Learning: Capturing Emerging Knowledge [PDF]

The process of strategy making presents a multi-faceted debate, with the ‘Learning School’ of strategic management being one of the main approaches to conceptualise strategy formation.
Oliver, John James, Rowles, Nicholas
core