Results 51 to 60 of about 101,680 (303)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Meikuang Anquan, 2021 Resilience can help miners cope with high-stress environment in coalmine production, and reduce their unsafe behavior. A moderated mediating model based on challenge model of resilience development was built with organizational justice as independent ...
PANG Xiaohua, LI Jizu
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Role of Organizational Commitment in Occupational Stress Models
, 2008 This study examined affective organizational commitment (AOC) and con- tinuance organizational commitment (COC) as moderators of the relation- ship between job-related anxiety and intention to leave among 506 Israeli nurses who completed self ...
Glazer, Sharon, Kruse, Bradford
core +1 more source
Shared identity in organizational stress and change [PDF]
Current Opinion in Psychology, 2018 The social identity approach has been found very useful for the understanding of a range of phenomena within and across organizations. It has been applied in particular to analyze employees' stress and well-being at work and their reactions to organizational change.
van Dick R., Ciampa V., Liang S.
openaire +4 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Relationship between Occupational Stress and Organizational Commitment among Staff Nurses [PDF]
Egyptian Journal of Health CareBackground : Occupational stress and Organizational commitment are very significant for ensuring sustained productivity from the employee of an organization.
Asmaa Mohammed Hamed +2 more
doaj +1 more source
THE INFLUENCE OF ORGANIZATIONAL CULTURE, JOB DEMANDS, AND COWORKERS TRUST ON JOB STRESS AND BURNOUT IN FIELD WORKERS OF OIL PALM PLANTATION COMPANIES IN THE PASER DISTRICT OF EAST KALIMANTAN [PDF]
Eurasia: Economics & Business, 2023 This study underscores the urgency of managing work stress, burnout, organizational culture, job demands, and trust among coworkers in the context of the palm oil industry.
Setyadi D., Paminto A., Adhimursandi D.
doaj