Results 81 to 90 of about 101,680 (303)

The Mediator Role of Organizational Support in the Relationship between Organizational Identity and Organizational Stress [PDF]

, 2020
The purpose of this research is to test the theoretical model developed for the mediator role of perceived organizational support in the relationship between organizational identity and organizational stress.
Ozgenel, Mustafa, Eksi, Halil, Demirci, Mehmed Esad   +2 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Stress on the Ward – An Empirical Study of the Nonlinear Relationship between Organizational Workload and Service Quality [PDF]

We discuss the impact of organizational workload on professional service outcomes, such as survival rates in hospitals. The prevailing view in the literature is that service quality deteriorates when organizational workload increases.
Ludwig Kuntz, Roman Mennicken, Stefan Scholtes   +2 more
core  

The Mediating Role of Job Stress in the Effect of Perceived Injustice on Cynicism Among Nurses in Türkiye: A Cross-Sectional Study

Ebelik ve Sağlık Bilimleri Dergisi
Objective: The aim of this study is to examine the effect of nurses' perceptions of organizational injustice on organizational cynicism and to investigate the mediating role of job stress.
Lokman Onur Ekinci, Ferhat Onur Ağaoğlu, Murat Baş   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Do you want me to be perfect? Two longitudinal studies on socially prescribed perfectionism, stress and burnout in the workplace [PDF]

, 2012
Stress and burnout in the workplace have a negative impact on organizations and customers and are estimated to cost the economy billions every year. To help identify employees at high risk, it is important to know what individual differences contribute ...
Stoeber, Joachim, Childs, Julian H.
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Perceived organizational support, organizational cynicism and employee well-being

, 2014
The present study examined how an employee’s perception of their employing organization can impact his or her thoughts, feelings and behaviors. This study examined cognitive, affective and behavioral organizational cynicism in relation to perceived ...
Peplinski, Marin Sara
core  

Examining the Relationship Between General Work Stress Levels and Organizational Identification Levels of Academics in Sports Sciences

Spor Bilimleri Araştırmaları Dergisi
The aim of this study is to examine the relationship between general work stress levels and organizational identification levels of academics working in the field of sports sciences.
Faik Orhun Tapşın, Sermin Ağralı Ermiş   +1 more
doaj   +1 more source