Results 31 to 40 of about 127,352 (253)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Predicting the Readiness for Organizational Change Based on Staff Perceptions about Organizational Structure Type with the Mediating Role of Organizational Integrity [PDF]

مطالعات مدیریت بهبود و تحول, 2015
The aim of this research was to predict the readiness for organizational change based on staff perceptions of organizational structure type with the mediating role of organizational integrity in a state bank.
Jafar Torkzade, Fatemeh Abdsharif
doaj  

Investigating the relationship between administrative automation with organizational agility and health, considering the mediating role of organizational structure dimensions [PDF]

رویکرد‌های نوین در مدیریت و بازاریابی
The purpose of this study is to examine the relationship between office automation and organizational agility and health, considering the mediating role of organizational structure dimensions.
Mohammadali Nikbakhsh, Behzad Sahraei, Ali Elaminezhad   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The Effective Factors on Knowledge Management in Universities from Physical Education Instructors’ Viewpoints

Physical Culture and Sport: Studies and Research, 2020
The aim of the present study was to investigate the relation of technology, organizational culture and emotional intelligence with knowledge management using the mediators of organizational structure and empowerment.
Shafiee Shahram, Eskandaripour Mojtaba, Soltani Samira   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Defining the Entropy of Hierarchical Organizations

Complexity, Governance & Networks, 2014
A measure of the order within a hierarchical organizational structure is proposed based on an analogy with the thermodynamic entropy of physical sciences. Organizational entropy is defined in a manner that readily allows for practical calculations.
David Chappell, T. Gregory Dewey
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

PRACTICAL ASPECTS OF EVALUATING THE EFFECTIVNESS OF THE INDUSTRIAL ENTERPRISE MANAGEMENT SYSTEM

Вестник университета, 2021
It is necessary to differentiate when considering the effectiveness of the organization’s management system: the organizational structure of management as a formalized descriptive scheme for the distribution of tasks and responsibilities and the ...
I. A. Stafeeva, E. M. Shironina
doaj   +1 more source