Results 121 to 130 of about 1,674,724 (292)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Consciência política e participação no Orçamento Participativo em Cachoeiro de Itapemirim (ES, 2009-2012)

Ciências Sociais Unisinos, 2015
The objective of this article is to understand the dynamics of political consciousness and citizen participation in Participatory Budgeting (PB) in Cachoeiro de Itapemirim (Espírito Santo State, Brazil) during 2009-2012.
Leandro Vianna Silva Souza, Marcia Prezotti Palassi, Alfredo Rodrigues Leite da Silva   +2 more
doaj  

O objeto objeto na análise organizacional: a teoria ator-rede como método de análise da participação dos não-humanos no processo organizativo

Cadernos EBAPE.BR
O objetivo deste artigo é analisar os objetos e elementos não-humanos como agentes constituintes do processo organizativo, por meio de uma abordagem pós-humanista: a teoria ator-rede.
César Tureta, Rafael Alcadipani
doaj   +1 more source

Beyond information: factors in participation in networks of practice, a case study of web management in UK Higher Education

, 2007
Purpose To explore the pattern and significance of cross-organizational ties in an emergent professional field, web production in UK Higher Education. Methodology/Approach The research is based on in-depth interviews with 21 practitioners and analysis
Cox, A.M.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The development of institutional theory in the field of organization studies in Brazil

Cadernos EBAPE.BR
This article is based on the assumption that the construction of scientific knowledge is a social process characterized by the recursive dynamic between the social and intellectual dimensions.
Edson Ronaldo Guarido Filho, Clóvis L. Machado-da-Silva   +1 more
doaj   +1 more source

Undisciplining Organizational Studies [PDF]

Journal of Management Inquiry, 1995
Ellen O'Connor, Mary Jo Hatch, Hayden V. White, Mayer N. Zald   +3 more
openaire   +1 more source

Why Should Organizational Scholars Study Migration?

Organization Science
Migration is one of the most significant forces shaping economies and societies, yet it remains largely understudied in organizational research. At the same time, scholars in other fields with long traditions of studying migration tend to overlook the essential role of organizations.
Exequiel Hernandez, Prithwiraj Choudhury, Elena Kulchina, Dan Wang, J. Myles Shaver, Mary Zellmer-Bruhn, Tarun Khanna   +6 more
openaire   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Appropriation and rationality in hip hop groups organization practices in Porto Alegre: an analysis on the perspective of Guerreiro Ramos

Cadernos EBAPE.BR
This paper discusses the organizational practices of hip hop groups from Porto Alegre, southern Brazil, as they appropriate foreign experience and rationally guide their social action.
Guilherme Dornelas Camara, Sueli Goulart, Rafaela Mendes Reinher   +2 more
doaj   +1 more source