Results 101 to 110 of about 691,724 (295)
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
ProductionPaper aims The main objective of this work is to integrate a typology of green supply chain management practices with organizational theories. Originality We provide a comprehensive typology of GSCM practices based on empirical evidence and conceptual ...
Jairo José Assumpção +4 more
doaj +1 more source
Defining and Assessing Organizational Culture [PDF]
, 2011 PROBLEM. Using theories from several disciplines, the concept of organizational culture remains controversial. Conflicting definitions, lack of semantic clarity, and debate over the most appropriate methods for assessing organizational culture have ...
Bellot PhD, RN, MHSA, Jennifer
core +2 more sources
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Путеводитель предпринимателяThe article presents a comprehensive analysis of the applicability of Douglas McGregor’s managerial assumptions — Theories X and Y — in the context of contemporary project–based activity and flexible organizational structures. The research is grounded in
K. V. Kulikov
doaj +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
The analysis and investigation of axiological presuppositions of organizational justice [PDF]
اسلام و مدیریتThis paper aimed at discovering, investigation and analysis of axiological foundations of organizational justice from the perspective of Islamic ethics. The existing disagreement between realists and anti-realists on the values has been known as the most
doaj
Issues in Managerial Compensation Research [PDF]
, 1995 [Excerpt] Compensation is at the core of any employment exchange (Milkovich & Newman, 1993; Simon, 1951). It is probably the most basic reason people agree to become employees and it serves as a defining characteristic of any employment relationship ...
Bloom, Matthew C. +1 more
core +1 more source