Results 91 to 100 of about 687,951 (314)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Concept of organized criminal group

open access: yes, 2012
Maģistra darbs ir veltīts organizētas grupas jēdzienam krimināltiesībās. Organizētās noziedzības problēma pasaulē kļūst arvien aktuālāka, līdzās citām negatīvām parādībām tā apdraud valstu drošību un ekonomisko attīstību. Autore sniedz vēsturisku atskatu
Fībiga, Vivita
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

[The OAR (Organized Against Racism) Report, The Issue of Racial Diversity at Sarah Lawrence College, July 1997]

open access: yes, 1997
The campus group of faculty, staff, and students, Organized Against Racism, shared this report on the findings of surveys and research aimed to determine whether racism exists here [at Sarah Lawrence] -- and if so, how it works and how it can be changed.
Organized Against Racism, Sarah Lawrence College
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The (Hidden) Financial Flows of Terrorist and Organized Crime Organizations: A Literature Review and Some Preliminary Empirical Results [PDF]

open access: yes
The financial means of international terror and organized crime organizations are analysed. First, some short remarks about the organization of international terror organizations are made.
Schneider, Friedrich
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Detecting organized eCommerce fraud using scalable categorical clustering

open access: yes, 2019
Kun artikkeli on julkaistu, selvitä mahdollinen embargo ja avaa tiedosto!!!Online retail, eCommerce, frequently falls victim to fraud conducted by malicious customers (fraudsters) who obtain goods or services through deception.
Marchal, Samuel, Szyller, Sebastian
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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