Results 91 to 100 of about 12,146,452 (311)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Other title: Supporting Ohio law enforcement
, 2011 "Protecting Ohio's Families."; "Mike DeWine, Ohio Attorney General."; "Created: 10/7/2011 ..."--Document properties screen.; Brochure; intended to be printed off on one sheet, front and back, and folded in thirds.; Harvested from the web on 10/24/13About
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Antea Group Archeologie 2019/200
, 2020 In opdracht van J.A. Rodenburg B.V. heeft Antea Group in november 2019 een archeologisch booronderzoek uitgevoerd op een perceel nabij de Denariusstraat 19 te Oosterhout.
Koopmanschap, Dr. H.J.L.C. (Antea Group) +7 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Antea Group Archeologie 2016/96
, 2016 In juli 2016 heeft Antea Group een archeologisch vooronderzoek uitgevoerd in de vorm van een archeologisch bureauonderzoek en een inventariserend veldonderzoek door middel van verkennende boringen.
Fens, drs. R.L. (Antea Group), R.L. Fens
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Antea Group Archeologie 2017/21
, 2017 In januari 2017 heeft Antea Group, in opdracht van Alliander N.V., een inventariserend veldonderzoek door middel van verkennende boringen uitgevoerd ten behoeve van een plangebied langs de zuidberm van de A15 tussen Ochten en Dodewaard in de gemeente ...
Teekens, Drs. P.C. (Antea group) +1 more
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
, 2019 Bakalaura darba temats “Organizēta grupa”. Noziedzīgi nodarījumi, kas izdarīti organizētā grupā gan Latvijā, gan pasaulē ir aktuāli jau kopš sākotnējo krimināltiesību institūtu rašanās, jo tieši organizētā grupā (t.i. – grupā bez iepriekšējas vienošanās,
Rēvalde, Patrīcija Kristijāna
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source