Results 111 to 120 of about 3,017,786 (307)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Criminal Associations: Insights into the Concept, Types, and Challenges for Legislative Improvements to Combat Them

Ученые записки Казанского университета: Серия Гуманитарные науки
This article suggests improvements to the criminal law measures against organized crime. The terminology and conceptual framework of criminal groups were analyzed using various methods, such as dialectical, comparative-legal, system-structural, and ...
I. Yu. Kufelkina
doaj   +1 more source

Group field theories

, 2011
Group field theories are particular quantum field theories defined on D copies of a group which reproduce spin foam amplitudes on a space-time of dimension D.
Krajewski, Thomas
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Renormalization group analysis of a continuous model with self-organized criticality: Effects of randomly moving environment

Nuclear Physics B
We study a strongly anisotropic self-organized critical system coupled to an isotropic random fluid environment. The former is described by a continuous (coarse-grained) model due to Hwa and Kardar.
N.V. Antonov, P.I. Kakin, N.M. Lebedev, A.Yu. Luchin   +3 more
doaj   +1 more source

The David and Lucile Packard Foundation OE Goldmine Research Project: Executive Summary [PDF]

, 2011
In response to growing demand for learning information from the nonprofit capacity?building field, the Packard Foundation launched the OE Goldmine Research Project to collect, organize, and analyze data from its OE Program in April 2010.

core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Features of cardiovascular risk in men and women of an organized group

Известия высших учебных заведений. Поволжский регион: Медицинские науки
Background. Chronic non-infectious diseases, primarily of the cardiovascular system, preserving leading positions among the causes of disability and mortality of the population in the world. The aim is to study individual factors of cardiovascular risk
Yu.A. Tomashevskaya, I.V. Avdeeva, P.M. Vasileva, E.I. Serikova, L.I. Salyamova   +4 more
doaj   +1 more source

Clinical research of organized stroke care model with integrated Chinese traditional and Western medicine in primary hospital

Chinese Journal of Contemporary Neurology and Neurosurgery, 2011
Objective To investigate the clinical effect of the organized stroke care model assisted with Chinese traditional medicine and acupuncture treatment for recovery in primary hospital.
Zhengbin PEI, Jinsheng ZHU, Rongbin HE, Zhilian PENG, Ansen YANG, Xuefeng ZHANG, Xin CHEN, Guofeng YU   +7 more
doaj  

Groups And Their Effects In Organizations

, 2015
The human is a social being and survives as the part of a group in every field of life from the birth. Group is a community consisting of one or more individuals who interact with each other in order to accomplish a certain goal. The groups are created formally and informally within the organization at different times and for different goals.
Aşçı, Mehmet Saim, Çemberci, Murat, Civelek, Mustafa Emre, Günel, Deniz   +3 more
openaire   +3 more sources