Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Highlights of the FEBS3+ meeting Exploring molecular frontiers. [PDF]
Dulić M, Koistinen H, Berntsson R.
europepmc +1 more source
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Impact of Artificial Intelligence for Detection of Precancerous Colonic Lesions in a Fecal Immunochemical Blood Test-Based Organized Screening Program in Italy: A Randomized Control Trial. [PDF]
Spada C +21 more
europepmc +1 more source
PROBLEMS OF ORGANIZING AGAINST ORGANIZED CRIMINAL GROUPS THREATENING STATE SECURITY OF UKRAINE
Yu.V. Lutsenko
openalex +1 more source
Report on 'Developments in deep‐fat frying for health and quality' ‐ organized by the SCI lipids group and supported by the food group [PDF]
Parkash Kochhar
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Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Effects of New Cellular Treatment Factor and Human Exosome Injection on Intact Skin Regeneration in a Randomized In Vivo Study. [PDF]
Adel N, Kolenda J.
europepmc +1 more source
Convergence of illegal organized armed groups in alluvial gold mining at the Department of Antioquia s Bajo Cauca subregion [PDF]
Isabel Esther Maldonado Sarmiento +1 more
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