Results 181 to 190 of about 687,951 (314)

Enhanced periodontal regeneration using formulated injectable hyaluronic acid with or without PRP: A rat ligature model. [PDF]

J Oral Biol Craniofac Res
Alghonemy WY, Ahmed NM, Abou Samra AA, Abdelfatah OM, Hanafy RA, Abd El-Aziz AM, Salem EM.   +6 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Older Adult Social Participation and Cognition: Illustrating Survey and Measurement Heterogeneity Across Studies. [PDF]

Res Aging
Vogelsang EM, Moorman S, Mijares A, Zanotelli Z, Ashtiani RT, Khani S.   +5 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Iterative Adaptations in a Physical Activity Program for Children with Autism: A Feasibility and Implementation Study. [PDF]

Healthcare (Basel)
Richter M, Taylor MK, Lindstedt T, Lundkvist Josenby A, Rask O, Ekdahl CT.   +5 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

BIDS-formatted resting-state and loudness dependence of auditory evoked potentials (LDAEP) EEG dataset from healthy women. [PDF]

Data Brief
Normannseth H, Andersson S, Hatlestad-Hall C.   +2 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Impact of the transition to HPV-based primary screening in Portugal's organized cervical cancer screening program: A controlled interrupted time-series analysis (2014-2023). [PDF]

Public Health Pract (Oxf)
Sousa R, Fonseca-Moutinho JA, Gomes F, Loureiro F, Goes AR, Soares P.   +5 more
europepmc   +1 more source