Results 201 to 210 of about 12,146,452 (311)

Examining the links between achievement goals, students' approaches to learning, and learning outcomes in business studies. [PDF]

Front Psychol
Ojala H, Tuominen H, Niemivirta M, Huikku J.   +3 more
europepmc   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

ASPIS Academy: A blueprint for building early-career researcher networks to advance NAM-based risk assessment. [PDF]

NAM J
Ladeira L, Martinez R, Hayot G, Islam B, Veltman CHJ, Sanz-Serrano J, Khalidi H, Ortega-Vallbona R, Corradi M, Cöllen E, Steinbach AM, Gabrišová K, Pôbiš P, Barnes D, Glasgow S, Niemeijer M, Zajac JD, Ormanin-Lewandowska A, Moné MJ, van de Water B, Colbourne JK, Vinken M, Tangianu S, Kandarova H, Pallocca G, Busquet F, Kuchovska E.   +26 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

A 3D-Bioprinted, Cell-Guiding Hydrogel Patch Promotes Functional Repair of Abdominal Incisions via Anisotropic ECM Remodeling. [PDF]

Smart Med
Gong T, Li H, Peng X, Liu X, Zhang X, Tang Q, Willerth S, Taba Junior M, Carvalho RM, Yu H, Wei S, Li H.   +11 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Trunk Muscle Performance, Spinal Alignment, and Postural Profiles in 9-11-Year-Old Children Participating in Intensively Organized Sport Assessed with Non-Radiographic Tools. [PDF]

Sports (Basel)
Sović I, Vučković M, Marijančić V, Hrlec M, Starčević-Klasan G, Grubić Kezele T, Kokot A.   +6 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Impact of Chile's Explicit Health Guarantees Policy on breast cancer mortality: an interrupted time series analysis (1990-2024). [PDF]

Front Oncol
Herrera MM, García-Calavaro C, Elorrieta F, Verdugo Sobral A, Toledo-Ordóñez I.   +4 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source