Results 61 to 70 of about 100,931 (277)

Multichannel detrended fluctuation analysis reveals synchronized patterns of spontaneous spinal activity in anesthetized cats.

PLoS ONE, 2011
The analysis of the interaction and synchronization of relatively large ensembles of neurons is fundamental for the understanding of complex functions of the nervous system. It is known that the temporal synchronization of neural ensembles is involved in
Erika E Rodríguez, Enrique Hernández-Lemus, Benjamín A Itzá-Ortiz, Ismael Jiménez, Pablo Rudomín   +4 more
doaj   +1 more source

The Organization of Intrinsic Computation: Complexity-Entropy Diagrams and the Diversity of Natural Information Processing

, 2008
Intrinsic computation refers to how dynamical systems store, structure, and transform historical and spatial information. By graphing a measure of structural complexity against a measure of randomness, complexity-entropy diagrams display the range and ...
Crutchfield, James P., Feldman, David P., McTague, Carl S.   +2 more
core   +1 more source

Designing for mathematical abstraction [PDF]

, 2010
Our focus is on the design of systems (pedagogical, technical, social) that encourage mathematical abstraction, a process we refer to as designing for abstraction.
Noss, Richard, Pratt, Dave
core   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Thermodynamics of Life as a Speculative Model for Planetary Technology

Technophany
Originating from nineteenth century physics, the concept of entropy—a measure of disorder, randomness, and/or the dissipation of useful energy—underlay a cosmology where order and complexity were seen as highly improbable phenomena in a universe tending
Cristian Hernandez-Blick
doaj   +1 more source

Accounting for regional background and population size in the detection of spatial clusters and outliers using geostatistical filtering and spatial neutral models: the case of lung cancer in Long Island, New York

International Journal of Health Geographics, 2004
Background Complete Spatial Randomness (CSR) is the null hypothesis employed by many statistical tests for spatial pattern, such as local cluster or boundary analysis. CSR is however not a relevant null hypothesis for highly complex and organized systems
Goovaerts Pierre, Jacquez Geoffrey M
doaj   +1 more source

Self - organized - criticality and synchronization in pulse coupled relaxation oscillator systems: the Olami, Feder and Christensen model and the Feder and Feder model

, 1996
We reexamine the dynamics of the Olami, Feder and Christensen (OFC) model. We show that, depending on the dissipation, it exhibits two different behaviors and that it can or cannot show self - organized - criticality (SOC) and/or synchronization. We also
Bottani, Samuele, Delamotte, Bertrand
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Advances in Unsteady Dynamics of Secondary Flow in 90° Pipe Bends [PDF]

长江科学院院报
[Objective] The unsteady motion of secondary flow, namely Dean vortices, in bent pipes can induce thermal fatigue and mechanical fatigue, posing a serious threat to the safe operation of industrial piping systems.
WANG Zhi-xin, HAN Song-lin, JIANG Zhi-bing
doaj   +1 more source