Results 121 to 130 of about 519,048 (295)
Power, Conflict, and Spirituality: A Qualitative Study of Faith-based Community Organizing
Community organizing is a process of garnering power and taking collective action which is often initiated by groups with little individual economic or social power.
Brian Christens +2 more
doaj
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
How emergent self organizing maps can help counter domestic violence. [PDF]
Topographic maps are an appealing exploratory instrument for discovering new knowledge from databases. During the past years, new types of Self Organizing Maps (SOM) were introduced in the literature, including the recent Emergent SOM.
Elzinga, Paul +4 more
core
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Performance enhanced by bridging the gap between theory and practice
Organizing Committee
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Human resource management implications of new forms of organizing [PDF]
Adopting a process view, we explore the personnel (HRM) implications of new forms of organizing (NFOs). We review the characteristics of NFOs and explain how they require a renewed HRM approach.
Sanchez-Runde, Carlos +2 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Curbing domestic violence: instantiating C-K theory with formal concept analysis and emergent self organizing maps. [PDF]
In this paper we propose a human-centered process for knowledge discovery from unstructured text that makes use of Formal Concept Analysis and Emergent Self Organizing Maps.
Elzinga, Paul +3 more
core
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source

