Results 131 to 140 of about 519,048 (295)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

International Conference MACHINES ET CALCULS UNIVERSELS\\ UNIVERSAL MACHINES AND COMPUTATIONS [PDF]

open access: yesComputer Science Journal of Moldova, 2000
ORGANIZING COMMITTEE
doaj  

ON THE NEED TO PREPARE STUDENTS OF REGIONAL DEVELOPMENT FOR ADMINISTRATIVE AND ORGANIZATIONAL SKILLS [PDF]

open access: yesJournal of Bio-Based Marketing
The article deals with discussion problems and views of the author on the problems of the formation of qualities and skills of future specialists in the field of regional development based on the changed environment and new pattern of global integration ...
Kamen Petrov
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Organizing Relationships Traditional and Emerging Perspectives on Workplace Relationships

open access: yes
Provides a comprehensive treatment, using multiple theoretical perspectives to understand and examine all workplace relationships.Cover -- Contents -- Preface -- 1 - Organizing Workplace Relationships -- 2 - Supervisor-Subordinate Relationships -- 3 ...
Sias, Patricia M.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Organizing in the Roman Empire

open access: yes, 2018
In her chapter, Czarniawska gives us the opportunity to imagine the origins of organizing in the still significant legacy of the Romans and their long-lasting empire.
Czarniawska, Barbara,
core  

Durvalumab-associated nephrotic syndrome and organizing pneumonia: a case report. [PDF]

open access: yesCEN Case Rep
Nawata T   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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