Results 81 to 90 of about 1,575,012 (307)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Family Engagement and Education: A Research Scan and Recommendations [PDF]

open access: yes, 2014
In September 2012, The Heinz Endowments asked the Annenberg Institute for School Reform (AISR) at Brown University to conduct a research scan of family engagement, leadership, and organizing work related to education happening in Pittsburgh, as a part of
Joanne Thompson   +4 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Under the Banner of Grief

open access: yesPerformance Philosophy
Grief is a radically social phenomenon that can be used to connect the unique experiences of individuals across space, time, and place. Organizers and activists within various social justice movements have used collective grief and public mourning to ...
Ash Williams
doaj   +1 more source

The Evolution of Strategic and Coordinated Bargaining Campaigns in the 1990s: The Steelworkers’ Experience [PDF]

open access: yes, 2001
With the refocusing of attention of the labor movement on organizing, an increasing number of scholars have been directing their research toward the nature and practice of current union organizing efforts.
Bronfenbrenner, Kate, Juravich, Tom
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Moving Stronger: Needs of the Criminal Justice Reform Movement [PDF]

open access: yes, 2001
Moving Stronger: Needs of the Criminal Justice Reform Movement presents the struggles, victories, strengths and challenges of grassroots groups organizing for criminal justice reform across the country.
Grace Chang, Ryan Pintado-Vertner
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Searching and organizing images across languages [PDF]

open access: yes, 2005
With the continual growth of users on the Web from a wide range of countries, supporting such users in their search of cultural heritage collections will grow in importance.
Clough, P., Sanderson, M., Shou, X.M.
core  

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