Results 81 to 90 of about 1,384 (194)

Orchestrating Relevance – Critique of a Questionable Trait of Modern Science Communication

CHIMIA
This essay critically analyzes the widespread phenomenon of claiming relevance when reporting original research. Specific examples from an area of method development in organofluorine chemistry demonstrate that the pursuit of worthiness of the ...
Antonio Togni
doaj   +1 more source

Origami with small molecules: exploiting the C–F bond as a conformational tool

Beilstein Journal of Organic Chemistry
When present within an organic molecule, the C–F bond tends to align in predictable ways with neighbouring functional groups, due to stereoelectronic effects such as hyperconjugation and electrostatic attraction/repulsion.
Patrick Ryan, Ramsha Iftikhar, Luke Hunter   +2 more
doaj   +1 more source

One-step introduction of the hexafluoroisobutyl group, synthesis of (S)-5,5,5,5',5',5'-hexafluoroleucine, and its incorporation into peptides and proteins

Comptes Rendus. Chimie
The isobutyl motif is a highly prevalent functional group in medicinal chemistry, commonly present in numerous drugs and bioactive compounds. In biological systems, it notably corresponds to the side chain of the amino acid leucine.
Delamare, Aline, Naulet, Guillaume, Mummadi, Sandeep, Guichard, Gilles, Compain, Guillaume   +4 more
doaj   +1 more source

Organo-fluorine chemistry III

Beilstein Journal of Organic Chemistry, 2013
David O'Hagan
doaj   +1 more source

Organo-fluorine chemistry II

Beilstein Journal of Organic Chemistry, 2010
David O'Hagan
doaj   +1 more source

Highly Site-Selective Formation of Perfluoroalkylated Anilids via a Protecting Strategy by Molybdenum Hexacarbonyl Catalyst

, 2019
Introducing a perfluoroalkyl group on the aromatic ring with high site selectivity remains a challenging area in organofluorine chemistry. We herein report a highly para-selective C–H perfluoroalkylation of aniline substrates using the molybdenum ...
Ping Dai (235336), Chunchen Yuan (3348158), Yingsheng Zhao (1528195), Xiaoguang Bao (1470508)   +3 more
core   +1 more source

1,4-Addition of the CF3 group, perfluoroalkyl groups and functionalized difluoromethylated moieties: An overview

, 2015
International audienceOver the last years, the organofluorine chemistry field has known a very fast expansion offering to the scientific community a panel of efficient tools for the synthesis of fluorinated molecules. Despite these recent advances, the 1,
Poisson, Thomas, Besset, Tatiana, Pannecoucke, Xavier   +2 more
core   +1 more source

Fluorinated natural compounds and synthetic drugs

, 2016
The driving force behind organofluorine chemistry is that carbonfluorine bonds impart unique characteristics to the molecules they form. Although not common in nature, organofluorines are encountered on a daily basis in items spanning from refrigerants ...
Niendorf, T., Ji, Y., Waiczies, S.
core  

Themed series in organo-fluorine chemistry

Beilstein Journal of Organic Chemistry, 2008
David O'Hagan
doaj   +1 more source

Trends in Organofluorine Chemistry Reveal Gaps in Knowledge on Environmental Persistence. [PDF]

Environ Sci Technol
Ng CA, King JF.
europepmc   +1 more source