Stage-Dependent Embryolethality of Diclofenac Sodium: Quantitative Assessment of Dose-Time Interaction and Critical Windows of Susceptibility in the In Ovo Chicken Embryo Model. [PDF]
Kizilay H, Rama ST.
europepmc +1 more source
Alternative Developmental Toxicity Screening Methods Using Chick Embryo‐Based Models
ABSTRACT Nonclinical developmental toxicity studies are used to investigate the potential toxicities of drugs and chemical candidates on normal embryonic and fetal development during pregnancy, generally using mammalian laboratory animals such as rats and rabbits.
Jeong Hwan Kim +4 more
wiley +1 more source
Evolutionary Repurposing of Cytokinin Signaling in Plant Development and Symbiosis. [PDF]
Zhang S, Jiang Y, Fang J, Wang T.
europepmc +1 more source
ABSTRACT Objective To assess the risk of major congenital anomalies (MCAs) and other adverse outcomes following prenatal exposure to modafinil. Methods This retrospective cohort study used the French national healthcare database (SNDS) to include singleton children born between January 2009 and September 2024 of women aged 15–55 years.
Melinda Kanoun +3 more
wiley +1 more source
Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley +1 more source
Unintended First-Trimester Exposure to Two Distinct Thrombopoietin Receptor Agonists in Consecutive Pregnancies Without Maternal or Fetal Harm [PDF]
Köseoğlu FD, Kum A.
europepmc +1 more source
ABSTRACT Pesticides and pharmaceuticals are among the most common chemical groups in waterbodies and soils, and their universal distribution raises concerns about potential adverse effects on nontarget organisms and humans. Reproductive output disruption is of particular concern, as it transposes effects from the individual to the next generations at ...
Fábio Campos +3 more
wiley +1 more source
Aspectos actuales de la organogénesis. Función e involución del timo
El timo es un órgano linfoide central o primario localizado en la parte anterosuperior del tórax. Constituye el principal sitio de diferenciación y maduración de las células T.
Vianed Marsán Suárez +2 more
doaj
Big data approaches to understanding gene regulatory networks in the shoot apical meristem and <i>de novo</i> shoot regeneration. [PDF]
Carpenter JH +3 more
europepmc +1 more source
Workflow for BICC1 interactome characterization in HEK293T cells. Cells expressing FLAG‐tagged BICC1 (full‐length or ΔSAM) were subjected to co‐immunoprecipitation under RNA‐preserved (−) or RNase‐treated (+) conditions (1). Interacting proteins were identified by LC–MS/MS (2) and analyzed through protein–protein interaction networks and functional ...
Heloísa Monteiro do Amaral‐Prado +7 more
wiley +1 more source

