FAM83H Regulates Postnatal T Cell Development Through Thymic Stroma Organization
Loss of the casein kinase 1 scaffolding protein FAM83H compromises bone marrow lymphopoiesis, reduces Foxn1 expression in cortical thymic epithelial cells (TEC), disrupts thymic architecture and TEC identity, and ultimately impairs double‐negative thymocyte proliferation and T‐cell production.
Betul Melike Ogan +16 more
wiley +1 more source
Influence of SARS-CoV-2 infection before and during organogenesis on embryo implantation and development outcomes: A prospective cohort observational study. [PDF]
Li Y +8 more
europepmc +1 more source
Self‐assembled liver organoids recapitulate hepatobiliary organogenesis in vitro
Dipen Vyas +8 more
semanticscholar +1 more source
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima +15 more
wiley +1 more source
Transgene-free mouse embryo models from chemical reprogramming reach early organogenesis. [PDF]
Yu X, Wang J.
europepmc +1 more source
Chd7 Is Critical for Early T-Cell Development and Thymus Organogenesis in Zebrafish [PDF]
Zhi-Zhi Liu +18 more
openalex +1 more source
Chitosan is highlighted for its industrial applications include food processing and preservation, pharmaceuticals, agriculture systems, and environmental protection. ABSTRACT Chitin, the natural biopolymer of the world next to cellulose, is a modified biodegradable polysaccharide.
Saeedeh Karimlar +4 more
wiley +1 more source
Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα [PDF]
Jana L. Mooster +10 more
openalex +1 more source
Role of Macrophages in Cardiac Remodeling: Cues From Zebrafish Heart
The figure illustrates the role of macrophage polarization in cardiac damage and repair, highlighting monocyte to M0, M1, and M2 macrophage differentiation. M1 macrophages, in response to pro‐inflammatory cytokines (e.g., IFNγ, TNF‐α, IL‐6), are involved in fibrosis and scarring in the heart.
Himanshu Gaur +2 more
wiley +1 more source
"Bud to bloom"-hormonal coordination in floral initiation. [PDF]
Baral R +4 more
europepmc +1 more source

