Epidemiology of Organophosphate Poisoning in the Tshwane District of South Africa
Background: Organophosphate poisoning is a major public health problem in South Africa. Individuals get exposed to organophosphate in both the domestic and industrial spheres.
LL Razwiedani, PGD Rautenbach
doaj +2 more sources
Pralidoxime for organophosphate poisoning
From their randomised trial, Kirti Pawar and colleagues report in today's Lancet on two pralidoxime-dosing schemes in 200 patients who had moderately severe self-poisoning with organophosphorus insecticide.1 After a 2-g loading dose over 30 min, half received a high-dose regimen of 1 g/h pralidoxime iodide for 48 h. The other half received a lower dose:
Eyer, Peter, Buckley, Nicholas
openaire +5 more sources
Organophosphorus compounds are very commonly available substance especially in agriculture based countries. Its use as a suicidal agent is rampant. Early management of the patient is critical in the final outcome. Use of atropine forms the mainstay of management after early decontamination. The role of oximes has been a matter of controversy.
Kathleen J, Richardson +2 more
openaire +3 more sources
An investigation of acute effects at various doses of malathion on glucose homeostasis and insulin resistance in rat liver, pancreas and serum [PDF]
Objective. This study investigates acute effects of various doses of Malathion on glucose homeostasis and insulin resistance in rat. Methods. Rats were randomly divided into four groups of 6 animals each. Corn oil was given orally to Group 1.
Ekremoğlu, Murat +4 more
core +3 more sources
Role of the Calcium Plateau in the Neuronal Injury and Behavioral Morbidities Following Organophosphate Intoxication [PDF]
Organophosphate (OP) chemicals include nerve agents and pesticides, and there is a growing concern of OP based chemical attacks against civilians. Current antidotes are essential in limiting immediate mortality associated with OP exposure.
Battaglia F.P. +8 more
core +2 more sources
Organophosphate intoxication via acetylcholinesterase inhibition executes neurotoxicity via hyper stimulation of acetylcholine receptors. Here, we use the organophosphate paraoxon-ethyl to treat C.
Patricia G Izquierdo +6 more
doaj +1 more source
Organophosphorus Compound Induced 'Intermediate Syndrome' [PDF]
Background: Organophosphate compound (OPC) poisoning with suicidal intent is common in Indian ICUs. These compounds are the organic derivatives of phosphorous containing acids and their effect on neuromuscular junction and autonomic synapses is ...
Tanuja Manohar, Harshal Khobragade
doaj +1 more source
Continuous renal replacement therapy increased plasma cholinesterase activity in a case of acute organophosphate poisoning [PDF]
Extracorporeal removal of organophosphate from blood has been proposed, but the efficacy of hemodialysis and hemoperfusion has not been established. We report a case of organophosphate poisoning in which continuous renal replacement therapy (CRRT) was ...
In Ho Kwon, Jinwoo Jeong, Yuri Choi
doaj +1 more source
Is pesticide exposure a cause of obstructive airways disease? [PDF]
Peer reviewedPublisher ...
Ayres, Jon G. +6 more
core +2 more sources
Effects of occupational exposure in pesticide plant on workers' serum and erythrocyte cholinesterase activity [PDF]
Objectives: The determination of cholinesterase activity has been commonly applied in the biomonitoring of exposure to organophosphates and carbamates and in the diagnosis of poisoning with anticholinesterase compounds.
Ahmadi, A.R. +2 more
core +1 more source

