Results 121 to 130 of about 16,948 (260)

Evaluation of cholinesterase level in workers exposed to organophosphates

, 2012
Background: Organophosphates use in agriculture and concern about their effects on human is increasing. This study was conducted to investigate the activity of blood cholinesterase in sprayers.
H Fallahzadeh, MH Mosadegh, SH Hekmati Moghaddam, T Raee Bandpey, A Barkhordri   +4 more
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Targeting of neurotrophic factors, their receptors, and signaling pathways in the developmental neurotoxicity of organophosphates in vivo and in vitro

, 2008
Neurotrophic factors control neural cell differentiation and assembly of neural circuits. We previously showed that organophosphate pesticides differentially regulate members of the fibroblast growth factor (fgf) gene family. We administered chlorpyrifos
F. Fumagalli, T. A. Slotkin, F. J. Seidler   +2 more
core   +1 more source

Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells

The Journal of Physiology, EarlyView.
Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski, Phetcharawan Lye, Enrrico Bloise, Stephen G. Matthews   +3 more
wiley   +1 more source

Rational design of paraoxonase 1 (PON1) for the efficient hydrolysis of organophosphates

, 2015
A rational design of paraoxonase 1 based on molecular docking discovered H115W/T332S and I74F/H115W/T332S mutants exhibited a 40-fold increase in catalytic efficiency (k(cat)/K-m) toward the hydrolysis of two toxic and popular organophosphates (diethyl ...
Kim, Yong Hwan, Chang, Rakwoo, Quang Anh Tuan Le   +2 more
core   +1 more source

Efficacy of Selected Commercial Bio‐Products in Disrupting Symbiont Acquisition and Survival of Halyomorpha halys (Hemiptera: Pentatomidae)

Entomologia Experimentalis et Applicata, Volume 174, Issue 7, Page 764-773, July 2026.
Targeting the symbiont Candidatus Pantoea carbekii offers a novel way to manage the invasive brown marmorated stink bug (Halyomorpha halys). Among the three commercial bio‐products tested, Dentamet significantly reduced symbiont acquisition and caused up to 75% nymphal mortality in laboratory conditions, which was confirmed by quantitative Real‐Time ...
Celal Tuncer, Abdullah Okan Seçer, I. Oguz Ozdemir, Göksel Özer, Mehtap Alkan, Matteo Masperro, Tommaso De Gregorio   +6 more
wiley   +1 more source

Phosphoryl Halogen and Hydrogen Bonding Controls the Solid‐State Structures of Aryl Halide‐Containing Phosphonates

European Journal of Inorganic Chemistry, Volume 29, Issue 17, 17 June 2026.
Intramolecular (RO)2PO→Halogen interaction versus intermolecular (RO)2PO···HOH hydrogen bonds. Although the O···I distance is shorter than the sum of the van der Waals radii of the atoms involved, there is no covalency involved in this interaction.
David Mross, Paweł Horeglad, Bastian Grabe, Wolf Hiller, Vito Lippolis, Massimiliano Arca, Klaus Jurkschat   +6 more
wiley   +1 more source

Nature's Nanotech Warriors: The Role of Metalloproteins and Protein Cages for Environmental Remediation

Advanced Sustainable Systems, Volume 10, Issue 6, June 2026.
Cartoon representation of five major classes of metalloproteins and their brief mechanisms of bioremediation. The five classes include metallothioneins, metal‐precipitating enzymes, P.‐type ATPases, protein cages, and synthetic metalloproteins (de novo‐designed proteins/peptides for selective adsorption). These natural and engineered protein structures
Sian D'Silva, Celin Acharya, Soumyananda Chakraborti   +2 more
wiley   +1 more source

Monoamine Oxidase and Cholinesterase Inhibition Profiles of Semicarbazone and Thiosemicarbazone Derivatives

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Thiosemicarbazones generally show higher MAO‐B inhibitory potential than their corresponding semicarbazones, and particularly T6 is the most potent, which contains R = H and X = S in its Tail Unit, with an IC50 value of 6.45 µM with SI of 3.6. ABSTRACT Twenty semicarbazone and thiosemicarbazone derivatives (T1–T20) were synthesized and evaluated for ...
Sandeep Bindra, Won Kyeong Jeong, Muzammil Kabier, Sunil Kumar, Sachithra Thazhathuveedu Sudevan, Harish Chandra vishwakarma, Della Grace Thomas Parambi, Naseer Maliyakkal, Sandeep Kumar, Leena K. Pappachen, Hoon Kim, Bijo Mathew   +11 more
wiley   +1 more source

Transcranial Direct Current Stimulation (tDCS) for the Treatment of Hemolacria Comorbid With Psychiatric and Somatic Symptoms: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Hemolacria is a rare condition characterized by bloody tears. Its etiology is often multifactorial, but functional/psychosomatic mechanisms have been proposed when organic causes are excluded. A 48‐year‐old woman with a history of multiple traumatic brain injuries (coma in 2008, car accident in 2017) presented with refractory generalized ...
Roghayeh Mohammadi, Ahmad Alipour
wiley   +1 more source

Organophosphates in Chlorpyrifos Insecticide: Neurobehavioral Development of Children in Agricultural Communities

, 2015
The chemicals found in fertilizers and pesticides are known to adversely affect the human nervous system even at low levels of exposure. Neither the agricultural industry nor the EPA can deny scientific findings regarding the toxic qualities of ...
Uppalapati, Sravya
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