Results 201 to 210 of about 16,948 (260)
Nephrotoxicity issues of organophosphates
Toxicology, 2018 Organophosphates are a large class of chemicals, initially invented in 1850 and since then they have been applied in numerous aspects of science to serve our purposes. Their mechanism of action in living organisms involves the irreversible inhibition of acetylcholinesterase, therefore they interfere with neuromuscular signal transmission.
G. Georgiadis +10 more
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Andrologia, 2021 Our purpose was to review and analyse the impact of pyrethroids and organophosphates exposure on human semen parameters. A comprehensive literature search was performed through MEDLINE via PubMed, Scopus and Webscience.
Carlo Giulioni +2 more
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Annals of Emergency Medicine, 1987
Organophosphate insecticides have become increasingly popular for agricultural, industrial, and home use and represent a significant potential health risk. We have reviewed the history, pathophysiology, clinical presentation, laboratory findings, differential diagnosis, therapy, and complications of toxic exposure to organophosphates. Promp recognition
J, Tafuri, J, Roberts
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Organophosphate insecticides have become increasingly popular for agricultural, industrial, and home use and represent a significant potential health risk. We have reviewed the history, pathophysiology, clinical presentation, laboratory findings, differential diagnosis, therapy, and complications of toxic exposure to organophosphates. Promp recognition
J, Tafuri, J, Roberts
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Organophosphates and the Heart
Chest, 1993(Chest 1993; 103:576-82) O rganophosphates are widely used as agricultural pesticides, and some of these compounds serve as nerve agents for chemical warfare. They act as powerful inhibitors of acetyicholinesterase, resulting in accumulation of acetylcholine and overstimulation ofcholinergic synapses in the central nervous system, somatic nerves ...
A, Roth +3 more
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Seminars in Neurology, 2004
Organophosphates are commonly used as pesticides around the world. Exposures to organophosphates cause a significant number of poisonings and deaths each year. Organophosphates bind and inhibit cholinesterase enzymes. Acute toxicity manifests as a cholinergic crisis with excessive glandular secretions, altered mental status, and weakness.
Daniel E, Rusyniak, Kristine A, Nañagas
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Organophosphates are commonly used as pesticides around the world. Exposures to organophosphates cause a significant number of poisonings and deaths each year. Organophosphates bind and inhibit cholinesterase enzymes. Acute toxicity manifests as a cholinergic crisis with excessive glandular secretions, altered mental status, and weakness.
Daniel E, Rusyniak, Kristine A, Nañagas
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Serum Albumin Binding and Esterase Activity: Mechanistic Interactions with Organophosphates [PDF]
Molecules, 2017 The albumin molecule, in contrast to many other plasma proteins, is not covered with a carbohydrate moiety and can bind and transport various molecules of endogenous and exogenous origin.
Nikolay V Goncharov +2 more
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Pharmacology of organophosphates
Journal of Applied Toxicology, 1994AbstractThe cholinergic nerve fibers, which employ acetylcholine (ACh) as a neurohumoral transmitter, and the results of their activation are listed. The reactions between the enzyme acetylcholinesterase (AChE), its natural substrate, ACh, and the various types of inhibitors are described.
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Pharmacology & Therapeutics, 1993
The present review discusses the structure of the anticholinesterase organophosphates (OPs), which are used predominantly as insecticides. OP poisoning can occur in a variety of situations and can be accidental or suicidal. It is common in developing countries.
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The present review discusses the structure of the anticholinesterase organophosphates (OPs), which are used predominantly as insecticides. OP poisoning can occur in a variety of situations and can be accidental or suicidal. It is common in developing countries.
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Organophosphates, Serine Esterase Inhibition, and Modeling of Organophosphate Toxicity
Toxicological Sciences, 2004The highlighted article in this issue (Ashani and Pistinner, "Estimation of the Upper Limit of Human Butyrylcholinesterase Dose Required for Protection against Organophosphates toxicity: A Mathematically Based Toxicokinetic Model") is an innovative approach to modeling the amount of protective enzyme, human butyrylcholinesterase, that could be ...
Janice, Chambers, Seth F, Oppenheimer
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