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South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1986 L L, Spruyt +3 more
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South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979 openaire +1 more source
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Seminars in Neurology, 2004
Organophosphates are commonly used as pesticides around the world. Exposures to organophosphates cause a significant number of poisonings and deaths each year. Organophosphates bind and inhibit cholinesterase enzymes. Acute toxicity manifests as a cholinergic crisis with excessive glandular secretions, altered mental status, and weakness.
Daniel E, Rusyniak, Kristine A, Nañagas
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Organophosphates are commonly used as pesticides around the world. Exposures to organophosphates cause a significant number of poisonings and deaths each year. Organophosphates bind and inhibit cholinesterase enzymes. Acute toxicity manifests as a cholinergic crisis with excessive glandular secretions, altered mental status, and weakness.
Daniel E, Rusyniak, Kristine A, Nañagas
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Annals of Emergency Medicine, 1987
Organophosphate insecticides have become increasingly popular for agricultural, industrial, and home use and represent a significant potential health risk. We have reviewed the history, pathophysiology, clinical presentation, laboratory findings, differential diagnosis, therapy, and complications of toxic exposure to organophosphates. Promp recognition
J, Tafuri, J, Roberts
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Organophosphate insecticides have become increasingly popular for agricultural, industrial, and home use and represent a significant potential health risk. We have reviewed the history, pathophysiology, clinical presentation, laboratory findings, differential diagnosis, therapy, and complications of toxic exposure to organophosphates. Promp recognition
J, Tafuri, J, Roberts
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Pharmacology & Therapeutics, 1993
The present review discusses the structure of the anticholinesterase organophosphates (OPs), which are used predominantly as insecticides. OP poisoning can occur in a variety of situations and can be accidental or suicidal. It is common in developing countries.
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The present review discusses the structure of the anticholinesterase organophosphates (OPs), which are used predominantly as insecticides. OP poisoning can occur in a variety of situations and can be accidental or suicidal. It is common in developing countries.
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Percutaneous Organophosphate Poisoning
Southern Medical Journal, 1987After cutaneous application of the organophosphate insecticide Diazinon for pubic lice, our patient had symptoms of cholinergic excess, lost consciousness, and had a seizure. Because of the high index of clinical suspicion for potentially lethal organophosphate poisoning, the patient received empiric therapy with pralidoxime and atropine and completely
A, Halle, D D, Sloas
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Organophosphate-Induced Delayed Polyneuropathy
Toxicological Reviews, 2005Organophosphate-induced delayed polyneuropathy (OPIDP) is a rare toxicity resulting from exposure to certain organophosphorus (OP) esters. It is characterised by distal degeneration of some axons of both the peripheral and central nervous systems occurring 1-4 weeks after single or short-term exposures.
M. Lotti, A. Moretto
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Organophosphate polyneuropathy
Neurology, 1984Organophosphorus-induced delayed polyneuropathy (OPIDP) is initiated by the phosphorylation of a protein neurotoxic esterase (NTE) in the nervous system. A second step, the "aging" of the phosphoryl-enzyme complex, is required to produce the toxic effect.
LOTTI, MARCELLO, BECKER CE, AMINOFF MJ
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Organophosphates, Serine Esterase Inhibition, and Modeling of Organophosphate Toxicity
Toxicological Sciences, 2004The highlighted article in this issue (Ashani and Pistinner, "Estimation of the Upper Limit of Human Butyrylcholinesterase Dose Required for Protection against Organophosphates toxicity: A Mathematically Based Toxicokinetic Model") is an innovative approach to modeling the amount of protective enzyme, human butyrylcholinesterase, that could be ...
Janice, Chambers, Seth F, Oppenheimer
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