Results 41 to 50 of about 2,501 (172)

Novel Human Butyrylcholinesterase Variants: Toward Organophosphonate Detoxication [PDF]

Biochemistry, 2014
Human butyrylcholinesterase (hBChE) is currently being developed as a detoxication enzyme for stoichiometric binding and/or catalytic hydrolysis of organophosphates. Herein, we describe the use of a molecular evolution method to develop novel hBChE variants with increased resistance to stereochemically defined nerve agent model compounds of soman ...
Dwyer, Mary, Javor, Sacha, Ryan, Daniel A., Smith, Emily M., Wang, Beilin, Zhang, Jun, Cashman, John R.   +6 more
openaire   +2 more sources

Synthesis of Polyhydroxylated Pyrrolidinyl Analogs of Sugar Nucleotides. Experimental and Computational Studies on Their Interactions With GalNAC‐T's

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
A multidisciplinary approach based on organic synthesis supported by quantum mechanical calculations, efficient phosphorylation methods, affinity studies using conventional techniques and saturation transfer difference nuclear magnetic resonance, together with molecular dynamics simulations, has enabled the preparation of nucleotide analogs with ...
Pedro Merino, Veronica Juste, Alejandro Montesa, Sandra Pereira, Sara Orta, Manuel Pedrón, Ana I. Jiménez, Sonsoles Martín‐Santamaría, Ramón Hurtado‐Guerrero, Ignacio Delso, Tomás Tejero   +10 more
wiley   +1 more source

Thermal desorption of dimethyl methylphosphonate from MoO₃ [PDF]

, 2017
Organophosphonates are used as chemical warfare agents, pesticides, and corrosion inhibitors. New materials for the sorption, detection, and decomposition of these compounds are urgently needed.
Ashley R. Head, Line Kyhl, Yu, Yi, Wang, Linjie, Zachariah, Michael, Michael Zachariah, Bluhm, Hendrik, Kit H. Bowen, Karslıoǧlu, Osman, Fears, Kenan, Zachary Hicks, Hannes Bleuel, Jeffrey Owrutsky, Hicks, Zachary, Owrutsky, Jeffrey, Lena Trotochaud, Osman Karslıoǧlu, Kenan Fears, Head, Ashley R, Scott Holdren, Bowen, Kit H, Kyhl, Line, Tang, Xin, Linjie Wang, Trotochaud, Lena, Holdren, Scott, Hendrik Bluhm, Bleuel, Hannes, Yi Yu, Xin Tang   +29 more
core   +1 more source

Amorphous Metallic Cobalt-Based Organophosphonic Acid Compounds as Novel Photocatalysts to Boost Photocatalytic CO₂ Reduction

C
Photocatalytic carbon dioxide conversion is a promising method for generating carbon fuels, in which the most important thing is to adjust the catalyst material to improve the photocatalytic efficiency and selectivity to conversion products, but it is ...
Chengwei Zhou, Fan Wu, Yonggong Tang, Boyuan Chai, Jiaxin Liang, Jiangang Han, Weinan Xing, Yudong Huang, Guangyu Wu   +8 more
doaj   +1 more source

Durable Physically Mixed Microporous and Mesoporous MOFs/Nanofiber Aerogel 3D Composites for Effective Toxic Gas Capture and Organophosphonate Detoxification

Advanced Functional Materials, Volume 36, Issue 13, 12 February 2026.
Ultralight 3D nanofibrous aerogels embedded with metal‐organic frameworks effectively capture and neutralize toxic gases and organophosphonates. Incorporating mesoporous UiO‐66‐NH2 and HKUST‐1 into PAN/PVP fibers enables high MOF loading while maintaining mechanical strength and structural stability.
Mai O. Abdelmigeed, Muhammed Ziauddin Ahmad Ebrahim, John J. Mahle, Brandon B. Blount, Gregory W. Peterson, Saad A. Khan, Gregory N. Parsons   +6 more
wiley   +1 more source

Lanthanide Coordination Networks Based on Diamantane‐4,9‐Diphosphonic Acid

Zeitschrift für anorganische und allgemeine Chemie, Volume 652, Issue 1, January 6, 2026.
The combination of Ln3+ ions and the diamantane‐4,9‐bis(hydrogenphosphonate) linker results in 3D networks where Eu3+, Gd3+, and Er3+ exhibit an uncommon coordination number of 6. Four new Ln‐based (Ln = Eu, Gd, Er) coordination networks, {[EuL1.5(H2O)4]·H2O}n and {[LnL1.5(H2O)]·H2O}n (Ln = Eu, Gd, Er), were synthesized using the precursor diamantane‐4,
Tim Müller, Peter Ferber, Philipp M. Roos, Nabil Assahub, Christoph Janiak   +4 more
wiley   +1 more source

Synthesis of Diaryl‐ and Dialkynylphosphinates From Ubiquitous PV Sources via a Redox‐Neutral Approach

Advanced Science, Volume 12, Issue 36, September 25, 2025.
Classical strategies for P─C bond formation rely on precursors (e.g., PH3, H2PO2, PCl3) obtained from P4, which is produced via the energy‐intensive thermal process. Here, an alternative, redox‐neutral approach is explored. Primary phosphate sources are activated with triflic anhydride (Tf2O) and 4‐dimethylaminopyridine (DMAP) to a versatile PV ...
Tobias Schneider, Kai Schwedtmann, Jannis Fidelius, Rosa M. Gomila, Antonio Frontera, Jan J. Weigand   +5 more
wiley   +1 more source

The utilization of aminoalkylphosphonic acids as sole nitrogen source by an environmental bacterial isolate [PDF]

, 1993
The synthetic organophosphonates 3‐aminopropylphosphonic acid and 4‐aminobutylphosphonic acid were utilized as sole nitrogen sources by an environmental bacterial isolate by a previously unreported pathway which did not involve cleavage of the carbon ...
Quinn, J. P., McMullan, G.; id_orcid
core   +1 more source

New Wine in Old Bottles: Fully Substituted Arylthio Effect Realizes High‐Efficiency Purely Organic Phosphorescence Light‐Emitting Diode With Single and Ultra‐Stable Spectra Under 2000 cd m−2

Aggregate, Volume 6, Issue 4, April 2025.
Benefiting from the fully substituted arylthio effect, pure organic emitter 6S has the most obvious aggregation‐induced phosphorescence characteristic, the largest spin orbital coupling value, and the smallest the energy gap between S1 and T1. Consequently, a high maximum external quantum efficiency of 15.3% and ultra‐stable spectra under high ...
Baijun Zhang, Baoxi Li, Han Zhang, Bingzhu Ma, Jingli Lou, Xiaobin Dong, Dezhi Yang, Ben Zhong Tang, Zhiming Wang   +8 more
wiley   +1 more source

Effects of glyphosate on antibiotic resistance in soil bacteria and its potential significance: A review

Journal of Environmental Quality, Volume 54, Issue 1, Page 160-180, January/February 2025.
Abstract The evolution and spread of antibiotic resistance are problems with important consequences for bacterial disease treatment. Antibiotic use in animal production and the subsequent export of antibiotic resistance elements in animal manure to soil is a concern.
Bradley L. Bearson, Cameron H. Douglass, Stephen O. Duke, Thomas B. Moorman, Patrick J. Tranel   +4 more
wiley   +1 more source