Results 21 to 30 of about 75,553 (267)

Thermostabilisation of human serum butyrylcholinesterase for detection of its inhibitors in water and biological fluids

Brazilian Archives of Biology and Technology, 1999
The ability of gelatine-trehalose to convert the normally fragile, dry human serum BChE into a thermostable enzyme and its use in the detection of cholinesterase inhibitors in water and biological fluids is described.
Lakshmanan Jaganathan, Rathanam Boopathy
doaj   +1 more source

Development of a Larval Zebrafish Model for Acute Organophosphorus Nerve Agent and Pesticide Exposure and Therapeutic Evaluation

Toxics, 2020
Organophosphorus compound exposure remains a present threat through agricultural accidents, warfare, or terrorist activity. The primary mechanism of organophosphorus toxicity is through inhibition of the enzyme acetylcholinesterase, with current ...
Jeffrey A. Koenig, Cindy Acon Chen, Tsung-Ming Shih   +2 more
doaj   +1 more source

Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme [PDF]

, 2010
Organophosphorus (OP) nerve agents are potent suicide inhibitors of the essential neurotransmitter-regulating enzyme acetylcholinesterase. Due to their acute toxicity, there is significant interest in developing effective countermeasures to OP ...
Andrew C. Hemmert, C. Linn Cadieux, Carol C. Edwards, Douglas M. Cerasoli, Fernando Rodrigues-Lima, John R. Cashman, Jonathan S. Edwards, Lyudmila Tsurkan, Matthew R. Redinbo, Monika Wierdl, Philip M. Potter, Roberto A. Chica, Shane A. Kasten, Stephen L. Mayo, Steven M. Lewis, Tamara C. Otto   +15 more
core   +6 more sources

Pattern, Management, and Outcome of Poisoning in a Tertiary Care Hospital

Journal of Lumbini Medical College, 2018
Introduction: Poisoning is a significant global public health problem. The appropriate management of poisoning at emergency needs accurate assessment and immediate treatment.
Naresh Karki, Vijay Singh, Vinod Kumar Verma   +2 more
doaj   +1 more source

Organophosphorus Chemistry 2021

Molecules, 2023
Forty years have passed since a real “phosphabenzene” (a phosphinine) was prepared for the first time applying steric protection methodology with the sterically demanding 2,4,6-tri-tertiary-butylphenyl (“supermesityl”) group [...]
openaire   +3 more sources

pH-Controlled Assembly of Five New Organophosphorus Strandberg-Type Cluster-Based Coordination Polymers for Enhanced Electrochemical Capacitor Performance.

Inorganic Chemistry, 2020
Cluster-based coordination polymers (CCPs) have shown promise as capacitors. To investigate the relativity between capacitor performance and crystal structure, herein, five new CCPs based on organophosphorus Strandberg-type clusters were synthesized via ...
Borong Lu, Shaobin Li, Jinghao Pan, Li Zhang, Jianjiao Xin, Yue Chen, Xiaoguo Tan   +6 more
semanticscholar   +1 more source

Phosphinate-containing heterocycles: A mini-review

Beilstein Journal of Organic Chemistry, 2014
This review provides an overview of recent efforts towards the synthesis of phosphinate heterocycles R1R2P(O)(OR). Our laboratory and others’ have been involved in this field and as a result new P–C, P–N, and P–O containing heterocyclic motifs are now ...
Olivier Berger, Jean-Luc Montchamp
doaj   +1 more source

Complexation of lithium and sodium cations with B-phosphorylate ethers, modelling terminal groups of organophosphorus podands. An experimental and theoretical study [PDF]

, 1992
The organophosphorus compounds o-Ph2P(O)C6H4OCH3 and Ph2P(O)C2H4OCH3, which are analogs of podands' terminal groups, have been synthesized. The thermodynamic characteristics of their complexation with LiNCS and NaNCS in acetonitrile were obtained by ...
Baulin, V.E., Elshof, J.E. ten, Glebov, A.S., Solovev, V.P., Tsvetkov, E.N., Varnek, A.A.   +5 more
core   +3 more sources

Resistance status of the carmine spider mite, Tetranychus cinnabarinus and the twospotted spider mite, Tetranychus urticae to selected acaricides on strawberries. [PDF]

, 2015
The carmine spider mite, Tetranychus cinnabarinus (Boisduval) and the twospotted spider mite, Tetranychus urticae Koch, are serious pests of strawberries and many other horticultural crops.
Bi, Jian-Long, Niu, Zi-Mian, Toscano, Nick C, Yu, Lu   +3 more
core   +1 more source

1-(3-Tert-Butylphenyl)-2,2,2-Trifluoroethanone as a Potent Transition-State Analogue Slow-Binding Inhibitor of Human Acetylcholinesterase: Kinetic, MD and QM/MM Studies

Biomolecules, 2020
Kinetic studies and molecular modeling of human acetylcholinesterase (AChE) inhibition by a fluorinated acetophenone derivative, 1-(3-tert-butylphenyl)-2,2,2-trifluoroethanone (TFK), were performed.
Irina V. Zueva, Sofya V. Lushchekina, Ian R. Pottie, Sultan Darvesh, Patrick Masson   +4 more
doaj   +1 more source