Pralidoxime in organophosphorus poisoning
INTRODUCTION: Pralidoxime are enzyme reactivator that are known to reactivate the phosphorylated acetylcholinesterase by binding to the organophosphorus molecule.
N R Simkhada, KK Kafle, PN Prasad
doaj +5 more sources
Acute poisoning by organophosphorus (OP) compounds is a major global clinical problem, with thousands of deaths occurring every year. Most of these pesticide poisoning and subsequent deaths occur in developing countries following a deliberate self ...
Buddhi Prasad Paudyal
doaj +5 more sources
Creatinephosphokinase in organophosphorus poisoning
Background: Organophosphorus Poisoning has been found to be a major cause of death or morbidity in our country as it freely available without need of prescription unlike in developed countries where prescription is required to purchase insecticides, the
Amith Kumar, V. Virupakshappa
semanticscholar +3 more sources
Organophosphorus Poisoning among Patients Admitted to the Intensive Care Unit of the Department of Internal Medicine in a Tertiary Care Centre: A Descriptive Cross-sectional Study [PDF]
Introduction: Organophosphates are potent cholinesterase inhibitors that when ingested in excessive amounts can be fatal. Organophosphorus poisoning has become an important clinical problem with increased mortality in the country from accidental or ...
Suzit Bhusal +6 more
doaj +2 more sources
Black Coloured Urine following Organophosphorus Poisoning: Report of Two Cases [PDF]
Organophosphorus poisoning is common in rural Asia. Clinical features result from overactivity of acetylcholine receptors. Blackish discoloration of urine is not a feature of organophosphorus poisoning.
Aneesh Basheer +4 more
doaj +2 more sources
Caspases as prognostic markers and mortality predictors in acute organophosphorus poisoning. [PDF]
Organophosphorus (OP) compounds have been widely available for decades in agriculture for crop protection and as cheap pest controllers, which increases the rate of exposure and poisoning cases.
Tallat S +4 more
europepmc +2 more sources
Trajectories of vital status parameters and risk of mortality among acute organophosphorus poisoning patients - a latent class growth analysis. [PDF]
Acute organophosphorus (OP) poisoning is one of the major causes of mortality among patients presenting to emergency departments in developing countries.
Farooqui WA +3 more
europepmc +2 more sources
Comparison of Acute Physiology, Age and Chronic Health Evaluation II score and Peradeniya Organophosphorus Poisoning Scale in predicting clinical outcomes and mortality in organophosphorus poisoning [PDF]
Background Organophosphorus poisoning is a major health hazard in developing countries. We conducted a study to compare the Acute Physiology, Age and Chronic Health Evaluation II (APACHE II) scoring system and Peradeniya Organophosphorus Poisoning Scale ...
Geo George Thomas +5 more
doaj +2 more sources
Correlation and prognostic significance of serum amylase, serum lipase, and plasma cholinesterase in acute organophosphorus poisoning. [PDF]
Background: Organophosphorus (OP) are substances that are originally produced by the reaction of alcohols and phosphoric acid. These OP compounds are the main components of herbicides, pesticides, and insecticides.
Dungdung A +5 more
europepmc +2 more sources
Recent developments on oximes to improve the blood brain barrier penetration for the treatment of organophosphorus poisoning: a review. [PDF]
Organophosphorus (OP) compounds are highly toxic synthetic compounds which have been used as pesticides and developed as warfare nerve agents. They represent a threat to both military and civilian populations.
Faiz Norrrahim MN +11 more
europepmc +2 more sources

