Results 11 to 20 of about 331 (157)

Metalloids: Semi as Metals yet Full of Antimicrobial Potential. [PDF]

ChemMedChem
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Böhm K, Nasim MJ, Jacob C.
europepmc   +2 more sources

Cytotoxic, Genotoxic, and Mutagenic Effects of Organotellurane RF07 in Female Swiss Mice (Mus musculus). [PDF]

Chem Biodivers
ABSTRACT The organotellurane RF07 (RF07) is an organic compound containing tellurium, a rare semi‐metal, and its leishmanicidal and antimalarial activity has already been reported in previous studies. This study evaluated the toxic effects of RF07 at 0.42, 21.37, and 42.75 mg/kg using comet assay, micronucleus test, and hematological/biochemical tests ...
de Jesus FEA, Maia OAC, de Lima RMT, de Meneses APM, Moura AS, Campinho Dos Reis A, Barreto do Nascimento MLL, Nobre TA, de Sousa AA, Coelho SGC, Marciel GLDS, Nolêto IRSG, Nunes AMV, Cunha RLOR, de Almeida PM, Felipe Ávila Alcantara DD, de Castro E Sousa JM.   +16 more
europepmc   +2 more sources

Synthesis, Biological Evaluation, and Molecular Docking of Tellurium-Containing Benzothiazole Derivatives as Enzyme Inhibitors of DNA Gyrase and Dihydrofolate Reductase. [PDF]

Biomed Res Int
Tellurium‐containing heterocycles represent an emerging class of organochalcogen compounds with notable redox properties and antimicrobial potential. Incorporation of tellurium into sulfur‐ and nitrogen‐containing frameworks can enhance biological activity through increased polarizability and favorable noncovalent interactions.
Haleha O, Pantyo V, Korol N, Danko E, Onysko M.   +4 more
europepmc   +2 more sources

Tellurophene-Induced Triplet-Singlet Spin-Flip Acceleration: An Advanced Design for Narrowband Organoboron Emitters with Fast Reverse Intersystem Crossing. [PDF]

Angew Chem Int Ed Engl
Linking an auxiliary dibenzo[b,d]tellurophene unit markedly accelerates exciton spin conversion in multi‐resonance‐type thermally activated delayed fluorescence emitters. Owing to the heavy‐atom effect of tellurium, the corresponding OLEDs retain remarkably high external electroluminescence quantum efficiencies exceeding 25% even at an exceptionally ...
Yang P, Lee JH, Urano K, Yasuda T.
europepmc   +3 more sources

Long-Range Supramolecular Synthon Isomerism: Insight from a Case Study of Vinylic Tellurium Trihalides Cl(Ph)C=C(Ph)TeX₃ (X = Cl, I)

Chemistry, 2022
A slight modification of the synthetic procedure resulted in a new (Cc) polymorph of vinylic tellurium-trichloride Z-Cl(Ph)C=C(Ph)TeCl3 (1, β-form) which is stabilized by Te⋯Cl chalcogen bonds, assembling its molecules into the zigzag chains.
Yury V. Torubaev, Aida S. Samigullina
doaj   +1 more source

The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition. [PDF]

PLoS ONE, 2016
BACKGROUND:The entry of HIV into its host cell is an interesting target for chemotherapeutic intervention in the life-cycle of the virus. During entry, reduction of disulfide bridges in the viral envelope glycoprotein gp120 by cellular oxidoreductases is
Kathrin Reiser, Leen Mathys, Sophie Curbo, Christophe Pannecouque, Sam Noppen, Sandra Liekens, Lars Engman, Mathias Lundberg, Jan Balzarini, Anna Karlsson   +9 more
doaj   +1 more source

Dihalogens Binding and Activation by Imidazoline-2-Chalcogenone Model Derivatives: Insight from a Computational Approach. [PDF]

Chemistry
1,3‐dimethyl‐4‐imidazoline‐2‐chalcogenones react with dihalogens, initially forming a charge‐transfer (CT) adduct, which may evolve to the most stable T‐shaped hypercoordinate (TY) species. However, in silico results show that the CT adduct is more stable than the corresponding TY species for the sulfur and iodine combination.
Zeppilli D, Madabeni A, Aragoni MC, Arca M, Orian L, Lippolis V.   +5 more
europepmc   +2 more sources

Maleic Anhydride and Its Derivatives: A Brief Review of Reactivity and Properties in Radical (Co)Polymerizations. [PDF]

Macromol Rapid Commun
Maleic anhydride (MAnh) and its derivatives are underutilized monomer classes, each with unique reactivities and properties, which afford the synthesis of highly functional (co)polymers. This review explores the current understanding, opportunities, and limitations associated with maleic anhydride and its derivatives in conventional radical and ...
Smith MP, Klumperman B.
europepmc   +2 more sources

Synthesis, DFT Calculation and Biological Activity of Some Organotellurium Compounds Containing Azomethine Group

Orbital: The Electronic Journal of Chemistry, 2019
The reaction of (4-amino-2,3-dichlorophenyl)mercury (II) chloride with 3,4-dihydroxy benzaldehyde produce the organomercury compound 1 in 82% yield. Tellurated of 1 with tellurium (IV) tetrabromide gave the tellurium (IV) tribromide Schiff base compound ...
Rafid Humiadan Al-Asadi
doaj   +3 more sources

Synthesis and Antimicrobial Evaluation of Some New Organic Tellurium Compounds Based on Pyrazole Derivatives

Molecules, 2020
A novel series of organic tellurium compounds based on pyrazole derivatives with a general formula of ArTeBr3 and Ar2TeBr2 [Ar = 2-(3-(4-substituted phenyl)-5-(2-chlorophenyl)-1H-pyrazol-1-yl)-3,5-dinitrophenyl] were obtained by the refluxing of ...
Asmaa B. Sabti, Adil A. Al-Fregi, Majeed Y. Yousif   +2 more
doaj   +1 more source