Results 1 to 10 of about 1,661,386 (133)

Antiviral Effect of 5′-Arylchalcogeno-3-aminothymidine Derivatives in SARS-CoV-2 Infection [PDF]

Molecules, 2023
The understanding that zidovudine (ZDV or azidothymidine, AZT) inhibits the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 and that chalcogen atoms can increase the bioactivity and reduce the toxicity of AZT has directed our search for the discovery ...
Amanda Resende Tucci, Raquel Mello da Rosa, Alice Santos Rosa, Otávio Augusto Chaves, Vivian Neuza Santos Ferreira, Thamara Kelcya Fonseca Oliveira, Daniel Dias Coutinho Souza, Nathalia Roberto Resende Borba, Luciano Dornelles, Nayra Salazar Rocha, João Candido Pilar Mayer, João B. Teixeira da Rocha, Oscar Endrigo D. Rodrigues, Milene Dias Miranda   +13 more
doaj   +2 more sources

An Efficient Method for the Selective Syntheses of Sodium Telluride and Symmetrical Diorganyl Tellurides and the Investigation of Reaction Pathways [PDF]

Molecules
Studies on organotellurium compounds have not been extensively conducted due to a lack of tolerable synthetic methods, difficult isolation processes, and their chemical instabilities.
Chorong Kim, Yoo Jin Lim, Ye Eun Kim, Akula S. N. Murthy, Hyunsung Cho, Hyejeong Lee, Myung-Sook Park, Sang Hyup Lee   +7 more
doaj   +2 more sources

Efficacy of selenium- and tellurium-based organocompounds against ruminant gastrointestinal nematodes in vitro [PDF]

Revista Brasileira de Parasitologia Veterinária
Gastrointestinal nematode (GIN) infections significantly impact the health of ruminants. The indiscriminate use of anthelmintics contributes to the selection of drug-resistant parasites.
Taynara Gabriele Ribeiro Piano, Irineu Romero Neto, Leandro Piovan, Leandro Bittencourt de Oliveira, Alda Lúcia Gomes Monteiro, Tay Zugman, Bernardo Ariel Schorr Zotz, Ursula Yaeko Yoshitani, Marcelo Beltrão Molento   +8 more
doaj   +3 more sources

SYNTHESIS OF NOVEL UNSATURATED ORGANOTELLURIUM COMPOUNDS WITH POTENTIAL BIOLOGICAL ACTIVITY [PDF]

Acta Biomedica Scientifica, 2012
Efficient synthetic approaches to novel organotellurium. compounds with potential biologically activity were elaborated, based, on acetylenes and tellurium, tetrahalid.es.
M. V. Musalova, V. A. Potapov, S. V. Amosova   +2 more
doaj   +1 more source

Oxidation Reactions Promoted or Catalyzed by Organotellurium Compounds [PDF]

ACS Omega
Philipe Raphael O. Campos, Guilherme P. P. P. Silva, Yuga Shibuya, Shinichi Koguchi, Eduardo E. Alberto   +4 more
doaj   +2 more sources

Organotellurium compounds as stabilizers for polymeric materials

, 1996
The thermal stability of a series of organotellurium compounds was determined by thermogravimetric analysis and the stabilizing capacity of the most heat-resistant compounds assessed in natural rubber, polyethylene, and polypropylene by measurement of ...
Stern, D,, Stenberg, B,, Engman, L,
core   +8 more sources

Metalloids: Semi as Metals yet Full of Antimicrobial Potential. [PDF]

ChemMedChem
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Böhm K, Nasim MJ, Jacob C.
europepmc   +2 more sources

Cytotoxic, Genotoxic, and Mutagenic Effects of Organotellurane RF07 in Female Swiss Mice (Mus musculus). [PDF]

Chem Biodivers
ABSTRACT The organotellurane RF07 (RF07) is an organic compound containing tellurium, a rare semi‐metal, and its leishmanicidal and antimalarial activity has already been reported in previous studies. This study evaluated the toxic effects of RF07 at 0.42, 21.37, and 42.75 mg/kg using comet assay, micronucleus test, and hematological/biochemical tests ...
de Jesus FEA, Maia OAC, de Lima RMT, de Meneses APM, Moura AS, Campinho Dos Reis A, Barreto do Nascimento MLL, Nobre TA, de Sousa AA, Coelho SGC, Marciel GLDS, Nolêto IRSG, Nunes AMV, Cunha RLOR, de Almeida PM, Felipe Ávila Alcantara DD, de Castro E Sousa JM.   +16 more
europepmc   +2 more sources

Synthesis, Biological Evaluation, and Molecular Docking of Tellurium-Containing Benzothiazole Derivatives as Enzyme Inhibitors of DNA Gyrase and Dihydrofolate Reductase. [PDF]

Biomed Res Int
Tellurium‐containing heterocycles represent an emerging class of organochalcogen compounds with notable redox properties and antimicrobial potential. Incorporation of tellurium into sulfur‐ and nitrogen‐containing frameworks can enhance biological activity through increased polarizability and favorable noncovalent interactions.
Haleha O, Pantyo V, Korol N, Danko E, Onysko M.   +4 more
europepmc   +2 more sources

Synthesis, Characterization and Theoretical Studies of New Organotellurium Compounds Based on (4-(((1S,E)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylidene)amino)phenyl)mercury(II) Chloride

Indonesian Journal of Chemistry, 2021
The current study aimed to prepare new organomercury and organotellurium compounds based on the condensation reaction of 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one (camphor) and p-aminophenyl mercuric(II) chloride.
Nuha Hussain Al-Saadawy
doaj   +1 more source