Results 1 to 10 of about 1,572,790 (175)

Oxidation Reactions Promoted or Catalyzed by Organotellurium Compounds [PDF]

ACS Omega
Oxidation of organic substrates is a pivotal transformation, with profound chemical and biological implications. This review covers the synthetic application of organotellurium compounds as promoters or activators of oxidizing agents in such reactions. This research field has evolved from utilizing stoichiometric amounts of organotellurium as oxidizing
Philipe Raphael O. Campos, Guilherme P. P. P. Silva, Yuga Shibuya, Shinichi Koguchi, Eduardo E. Alberto   +4 more
doaj   +4 more sources

Antiviral Effect of 5′-Arylchalcogeno-3-aminothymidine Derivatives in SARS-CoV-2 Infection [PDF]

Molecules, 2023
The understanding that zidovudine (ZDV or azidothymidine, AZT) inhibits the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 and that chalcogen atoms can increase the bioactivity and reduce the toxicity of AZT has directed our search for the discovery ...
Amanda Resende Tucci, Raquel Mello da Rosa, Alice Santos Rosa, Otávio Augusto Chaves, Vivian Neuza Santos Ferreira, Thamara Kelcya Fonseca Oliveira, Daniel Dias Coutinho Souza, Nathalia Roberto Resende Borba, Luciano Dornelles, Nayra Salazar Rocha, João Candido Pilar Mayer, João B. Teixeira da Rocha, Oscar Endrigo D. Rodrigues, Milene Dias Miranda   +13 more
doaj   +2 more sources

Metalloids: Semi as Metals yet Full of Antimicrobial Potential. [PDF]

ChemMedChem
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Böhm K, Nasim MJ, Jacob C.
europepmc   +2 more sources

An Efficient Method for the Selective Syntheses of Sodium Telluride and Symmetrical Diorganyl Tellurides and the Investigation of Reaction Pathways [PDF]

Molecules
Studies on organotellurium compounds have not been extensively conducted due to a lack of tolerable synthetic methods, difficult isolation processes, and their chemical instabilities.
Chorong Kim, Yoo Jin Lim, Ye Eun Kim, Akula S. N. Murthy, Hyunsung Cho, Hyejeong Lee, Myung-Sook Park, Sang Hyup Lee   +7 more
doaj   +2 more sources

Cytotoxic, Genotoxic, and Mutagenic Effects of Organotellurane RF07 in Female Swiss Mice (Mus musculus). [PDF]

Chem Biodivers
ABSTRACT The organotellurane RF07 (RF07) is an organic compound containing tellurium, a rare semi‐metal, and its leishmanicidal and antimalarial activity has already been reported in previous studies. This study evaluated the toxic effects of RF07 at 0.42, 21.37, and 42.75 mg/kg using comet assay, micronucleus test, and hematological/biochemical tests ...
de Jesus FEA, Maia OAC, de Lima RMT, de Meneses APM, Moura AS, Campinho Dos Reis A, Barreto do Nascimento MLL, Nobre TA, de Sousa AA, Coelho SGC, Marciel GLDS, Nolêto IRSG, Nunes AMV, Cunha RLOR, de Almeida PM, Felipe Ávila Alcantara DD, de Castro E Sousa JM.   +16 more
europepmc   +2 more sources

Efficacy of selenium- and tellurium-based organocompounds against ruminant gastrointestinal nematodes in vitro [PDF]

Revista Brasileira de Parasitologia Veterinária
Gastrointestinal nematode (GIN) infections significantly impact the health of ruminants. The indiscriminate use of anthelmintics contributes to the selection of drug-resistant parasites.
Taynara Gabriele Ribeiro Piano, Irineu Romero Neto, Leandro Piovan, Leandro Bittencourt de Oliveira, Alda Lúcia Gomes Monteiro, Tay Zugman, Bernardo Ariel Schorr Zotz, Ursula Yaeko Yoshitani, Marcelo Beltrão Molento   +8 more
doaj   +3 more sources

Synthesis, Biological Evaluation, and Molecular Docking of Tellurium-Containing Benzothiazole Derivatives as Enzyme Inhibitors of DNA Gyrase and Dihydrofolate Reductase. [PDF]

Biomed Res Int
Tellurium‐containing heterocycles represent an emerging class of organochalcogen compounds with notable redox properties and antimicrobial potential. Incorporation of tellurium into sulfur‐ and nitrogen‐containing frameworks can enhance biological activity through increased polarizability and favorable noncovalent interactions.
Haleha O, Pantyo V, Korol N, Danko E, Onysko M.   +4 more
europepmc   +2 more sources

Broadly Defined Antibiotic Adjuvants for <i>Pseudomonas aeruginosa</i>. [PDF]

Can J Infect Dis Med Microbiol
Pseudomonas aeruginosa is a widely distributed opportunistic pathogen with multiple drug resistance, making it particularly challenging to treat in lower respiratory tract infections. Its resistance mechanisms are complex, including low outer‐membrane permeability, efflux pump overexpression, biofilm formation, and quorum sensing (QS) activation ...
Chen Z, Li Y, Song Y.
europepmc   +2 more sources

Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems. [PDF]

Chem Rec
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Ramírez RER, Almeida TM, Leite DC, Zeni G.   +3 more
europepmc   +2 more sources

Chalcogen-Guided Control of Azoarene Photoswitching: Tuning Excited-State Energies Through Electronic Property Modulation. [PDF]

Chemistry
Photophysical properties of ortho‐tellurium‐substituted azoarenes are tunable via aryl substituent electronics and tellurium oxidation state. Electron‐donating groups destabilize the excited state three‐electron σ bond, enhancing photoisomerization.
Scheller ZN, Schulte J, Wölper C, Haberhauer G.   +3 more
europepmc   +2 more sources