Results 11 to 20 of about 302 (145)

Metalloids: Semi as Metals yet Full of Antimicrobial Potential. [PDF]

ChemMedChem
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Böhm K, Nasim MJ, Jacob C.
europepmc   +2 more sources

Cytotoxic, Genotoxic, and Mutagenic Effects of Organotellurane RF07 in Female Swiss Mice (Mus musculus). [PDF]

Chem Biodivers
ABSTRACT The organotellurane RF07 (RF07) is an organic compound containing tellurium, a rare semi‐metal, and its leishmanicidal and antimalarial activity has already been reported in previous studies. This study evaluated the toxic effects of RF07 at 0.42, 21.37, and 42.75 mg/kg using comet assay, micronucleus test, and hematological/biochemical tests ...
de Jesus FEA, Maia OAC, de Lima RMT, de Meneses APM, Moura AS, Campinho Dos Reis A, Barreto do Nascimento MLL, Nobre TA, de Sousa AA, Coelho SGC, Marciel GLDS, Nolêto IRSG, Nunes AMV, Cunha RLOR, de Almeida PM, Felipe Ávila Alcantara DD, de Castro E Sousa JM.   +16 more
europepmc   +2 more sources

Synthesis, Biological Evaluation, and Molecular Docking of Tellurium-Containing Benzothiazole Derivatives as Enzyme Inhibitors of DNA Gyrase and Dihydrofolate Reductase. [PDF]

Biomed Res Int
Tellurium‐containing heterocycles represent an emerging class of organochalcogen compounds with notable redox properties and antimicrobial potential. Incorporation of tellurium into sulfur‐ and nitrogen‐containing frameworks can enhance biological activity through increased polarizability and favorable noncovalent interactions.
Haleha O, Pantyo V, Korol N, Danko E, Onysko M.   +4 more
europepmc   +2 more sources

Chalcogen-Guided Control of Azoarene Photoswitching: Tuning Excited-State Energies Through Electronic Property Modulation. [PDF]

Chemistry
Photophysical properties of ortho‐tellurium‐substituted azoarenes are tunable via aryl substituent electronics and tellurium oxidation state. Electron‐donating groups destabilize the excited state three‐electron σ bond, enhancing photoisomerization.
Scheller ZN, Schulte J, Wölper C, Haberhauer G.   +3 more
europepmc   +2 more sources

Dihalogens Binding and Activation by Imidazoline-2-Chalcogenone Model Derivatives: Insight from a Computational Approach. [PDF]

Chemistry
1,3‐dimethyl‐4‐imidazoline‐2‐chalcogenones react with dihalogens, initially forming a charge‐transfer (CT) adduct, which may evolve to the most stable T‐shaped hypercoordinate (TY) species. However, in silico results show that the CT adduct is more stable than the corresponding TY species for the sulfur and iodine combination.
Zeppilli D, Madabeni A, Aragoni MC, Arca M, Orian L, Lippolis V.   +5 more
europepmc   +2 more sources

Maleic Anhydride and Its Derivatives: A Brief Review of Reactivity and Properties in Radical (Co)Polymerizations. [PDF]

Macromol Rapid Commun
Maleic anhydride (MAnh) and its derivatives are underutilized monomer classes, each with unique reactivities and properties, which afford the synthesis of highly functional (co)polymers. This review explores the current understanding, opportunities, and limitations associated with maleic anhydride and its derivatives in conventional radical and ...
Smith MP, Klumperman B.
europepmc   +2 more sources

In vitro and in vivo activity of an organic tellurium compound on Leishmania (Leishmania) chagasi. [PDF]

PLoS ONE, 2012
Tellurium compounds have shown several biological properties and recently the leishmanicidal effect of one organotellurane was demonstrated. These findings led us to test the effect of the organotellurium compound RF07 on Leishmania (Leishmania) chagasi,
Isabella Aparecida Salerno Pimentel, Carolina de Siqueira Paladi, Simone Katz, Wagner Alves de Souza Júdice, Rodrigo L O R Cunha, Clara Lúcia Barbiéri   +5 more
doaj   +1 more source

Synthesis, DFT Calculation and Biological Activity of Some Organotellurium Compounds Containing Azomethine Group

Orbital: The Electronic Journal of Chemistry, 2019
The reaction of (4-amino-2,3-dichlorophenyl)mercury (II) chloride with 3,4-dihydroxy benzaldehyde produce the organomercury compound 1 in 82% yield. Tellurated of 1 with tellurium (IV) tetrabromide gave the tellurium (IV) tribromide Schiff base compound ...
Rafid Humiadan Al-Asadi
doaj   +3 more sources

Xerogel-Sequestered Silanated Organochalcogenide Catalysts for Bromination with Hydrogen Peroxide and Sodium Bromide

Molecules, 2015
While H2O2 is a powerful oxidant, decomposing into environmentally benign H2O and O2, a catalyst is often required for reactions with H2O2 to proceed at synthetically useful rates.
Caitlyn M. Gatley, Lisa M. Muller, Meredith A. Lang, Eduardo E. Alberto, Michael R. Detty   +4 more
doaj   +1 more source

Protective effect of the organotelluroxetane RF-07 in pilocarpine-induced status epilepticus

Neurobiology of Disease, 2008
Temporal lobe epilepsy is the most common form of epilepsy in humans. Caspase activation is a mechanism of cell death induced by seizures. Tellurium (IV) compounds present antitumoral, immunomodulatory and neuroprotective effects due to their ability to ...
Daniele Suzete Persike, Rodrigo Luiz Oliveira Rodrigues Cunha, Luiz Juliano, Iara Ribeiro Silva, Fernanda Elisa Rosim, Thiago Vignoli, Flavia Dona, Esper Abrão Cavalheiro, Maria José da Silva Fernandes   +8 more
doaj   +1 more source