Results 31 to 40 of about 11,874 (219)

Divergent strategy for the synthesis of α-aryl-substituted fosmidomycin analogues [PDF]

, 2007
Fosmidomycin is the first representative of a new class of antimalarial drugs acting through inhibition of 1-deoxy-D-xylulose 5-phosphate ( DOXP) reductoisomerase (DXR), an essential enzyme in the non-mevalonate pathway for the synthesis of isoprenoids ...
Devreux, Vincent, Jomaa, Hassan, Rozenski, Jef, Van Calenbergh, Serge, Van der Eycken, Johan, Wiesner, Jochen   +5 more
core   +2 more sources

The bromotyrosine derivative Ianthelline isolated from the Arctic marine sponge Stryphnus fortis inhibits marine micro- and macrobiofouling [PDF]

, 2014
International audienceThe inhibition of marine biofouling by the bromotyrosine derivative ianthelline, isolated from the Arctic marine sponge Stryphnus fortis, is described. All major stages of the fouling process are investigated.
Andersen, Jeanette H., Cervin, Gunnar, Hansen, Espen, Hanssen, Kine Ø., Haug, Tor, Hellio, Claire, Pavia, Henrik, Petitbois, Julie, Svenson, Johan, Trepos, Rozenn   +9 more
core   +3 more sources

Dynamic modelling of a fractionation process for a liquid mixture using supercritical carbon dioxide [PDF]

, 2001
This work presents a simple dynamic modelling of a process of separation of a quaternary mixture using supercritical CO2. Thermodynamic description is accomplished using efficient available models (SRK equation of state with MHV2 mixing rules).
Abrams, Cesari, Choi, Chrisochoou, Chrisochoou, Comelli, Gear, Hindmarsch, Jean-Stéphane Condoret, Jessop, Kizlink, Kizlink, Michelsen, Rachford, Redlich, Sakakura, Soave, Séverine Camy, Yoon   +18 more
core   +3 more sources

Biotransformation of butyltin compounds and microbiome diversity in the bottom sediments of the Gulf of Finland, the Baltic Sea

Трансформация экосистем
Pollution of the marine environment with organotin compounds is a serious environmental problem due to their extreme toxicity to a wide range of organisms.
Kuzikova I.L., Zhakovskaya Z.A., Medvedeva N.G.   +2 more
doaj   +1 more source

Imposex in Plicopurpura pansa (Neogastropoda: Thaididae) in Nayarit and Sinaloa, Mexico

Revista Mexicana de Biodiversidad, 2015
Imposex is the development of male features in female prosobranch gastropods, caused by organotin compounds. In the Mexican Pacific coast, imposex was observed in Plicopurpura pansa.
Delia Domínguez-Ojeda, Olga Araceli Patrón-Soberano, José Trinidad Nieto-Navarro, María de Lourdes Robledo-Marenco, Jesús Bernardino Velázquez-Fernández   +4 more
doaj   +1 more source

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Organotin(IV) derivatives with 5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidine and their cytotoxic activities: the importance of being conformers. [PDF]

, 2014
The organotin(IV) compounds Me2SnCl2(dbtp)(1), Me2SnCl2(dbtp)2 (2), Et2SnCl2(dbtp) (3), Et2SnCl2(dbtp)2 (4), Et2SnCl2(dptp) (5), nBu2SnCl2(dbtp)2 (6), nBu2SnCl2(dptp) (7), Ph2SnCl2(dbtp) (8), Ph2SnCl2(dptp)2 (9), where dbtp = 5,7-di-tert-butyl-1,2,4 ...
Alessandro Attanzio, Bond, Bratton, Brittain, Cooney, Crowe, Davies, Denizot, Duisenberg, Duisenberg, Giancarlo Stocco, Girasolo, Girasolo, Hadjikakou, Hammill, Ianelli, Luisa Tesoriere, Maria Assunta Girasolo, Nangia, Navarro, Pellerito, Piera Sabatino, Ruan, Ruiz, Salas, Saxena, Shang, Shang, Sheldrick, Sheldrick, Simona Rubino, Tabassum, Velders, Wishweshwar, Yin, Łakomska, Łakomska   +36 more
core   +1 more source

Biological Evaluation of Triorganotin Derivatives as Potential Anticancer Agents

Molecules, 2023
Metal-derived platinum complexes are widely used to treat solid tumors. However, systemic toxicity and tumor resistance to these drugs encourage further research into similarly effective compounds.
Valeria Stefanizzi, Antonella Minutolo, Elena Valletta, Martina Carlini, Franca M. Cordero, Anna Ranzenigo, Salvatore Pasquale Prete, Daniel Oscar Cicero, Erica Pitti, Greta Petrella, Claudia Matteucci, Francesca Marino-Merlo, Antonio Mastino, Beatrice Macchi   +13 more
doaj   +1 more source

Tributyltin Protumorigenic Effects Targeting Prostate Cancer Cell Metabolism, Proliferation, Migration, and Invasion

Environmental Toxicology, EarlyView.
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó, Luís P. Brás, Catarina M. D. Serra, Lara R. S. Fonseca, Sara Correia, Bruno J. Pereira, Ana P. Duarte, Henrique J. Cardoso, Cátia V. Vaz, Sílvia Socorro   +9 more
wiley   +1 more source

Ionic Liquid Supported Organotin Reagents: Green Tools for Stille Cross-Coupling Reactions with Brominated Substrates [PDF]

, 2011
Efficiency of ionic liquid supported organotin reagents in Stille cross-coupling reactions involving aryl bromides has been investigated. In a general manner, products were isolated with good yields by using a very simple catalytic system without the ...
A.S. Castanet, D. Faye, F. Boeda, N. Louaisil, P.Dien Pham, S. Legoupy   +5 more
core   +3 more sources