Results 21 to 30 of about 3,441,522 (187)

Developmental dynamics of lncRNAs across mammalian organs and species

Nature, 2019
Although many long noncoding RNAs (lncRNAs) have been identified in human and other mammalian genomes, there has been limited systematic functional characterization of these elements.
Ioannis Sarropoulos, Ray Marin, Margarida Cardoso-Moreira, H. Kaessmann   +3 more
semanticscholar   +1 more source

Computational design of artificial organs [PDF]

, 2008
C
De Beule, Matthieu, Verdonck, Pascal
core   +1 more source

Tertiary lymphoid organs in central nervous system autoimmunity [PDF]

, 2016
Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients.
Mitsdoerffer, M., Peters, A.
core   +1 more source

Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude

Nature Communications, 2018
Drug delivery by nanocarriers (NCs) has long been stymied by dominant liver uptake and limited target organ deposition, even when NCs are targeted using affinity moieties.
J. Brenner, Daniel C. Pan, J. Myerson, O. Marcos-Contreras, C. Villa, Priyal Patel, Hugh Hekierski, S. Chatterjee, J. Tao, H. Parhiz, Kartik Bhamidipati, Thomas Uhler, E. Hood, R. Kiseleva, Vladimir S. Shuvaev, T. Shuvaeva, M. Khoshnejad, Ian H Johnston, Jason V. Gregory, J. Lahann, Tao Wang, E. Cantu, W. Armstead, S. Mitragotri, V. Muzykantov   +24 more
semanticscholar   +1 more source

Glutathione increase by the n-butanoyl glutathione derivative (GSH-C4) inhibits viral replication and induces a predominant Th1 immune profile in old mice infected with influenza virus [PDF]

, 2019
During aging, glutathione (GSH) content declines and the immune system undergoes a deficiency in the induction of Th1 response. Reduced secretion of Th1 cytokines, which is associated with GSH depletion, could weaken the host defenses against viral ...
Amatore, D, Brundu, S, Celestino, I, Checconi, P, Coluccio, P, Fraternale, A, Galluzzi, L, Magnani, M, Nencioni, L, Palamara, A. T.   +9 more
core   +1 more source

FDISCO: Advanced solvent-based clearing method for imaging whole organs

Science Advances, 2019
We developed an advanced clearing method with superior fluorescence-preserving capability for 3D imaging of whole organs. Various optical clearing methods have emerged as powerful tools for deep biological imaging. Organic solvent–based clearing methods,
Yisong Qi, Tingting Yu, Jianyi Xu, Peng Wan, Yilin Ma, Jingtan Zhu, Yusha Li, H. Gong, Qingming Luo, D. Zhu   +9 more
semanticscholar   +1 more source

Organs and universities: a universal association? [PDF]

, 2013
Short essay on the association between organs and ...
Butt, J.
core  

In vivo analysis of staphylococcus aureus-infected mice reveals differential temporal and spatial expression patterns of fhuD2 [PDF]

, 2017
Staphylococcus aureus is an opportunistic human pathogen and a major cause of invasive infections such as bacteremia, endocarditis, pneumonia and wound infections.
Bacconi, Marta, Bagnoli, Fabio, Bensi, Giuliano, Chiarot, Emiliano, Delany, Isabel, Donato, Paolo, Freitag, Nancy E., Haag, Andreas F.   +7 more
core   +1 more source

Tissue residency of innate lymphoid cells in lymphoid and nonlymphoid organs

Science, 2015
Establishing a longtime residency Innate lymphoid cells (ILCs) are a subset of immune cells that promote barrier immunity in tissues such as the gut and lungs and help to maintain immune homeostasis. Gasteiger et al.
G. Gasteiger, Xiying Fan, Stanislav Dikiy, Sue Y. Lee, A. Rudensky   +4 more
semanticscholar   +1 more source

Editorial: tertiary lymphoid organs (TLOs): powerhouses of disease immunity [PDF]

, 2017
No abstract ...
Habenicht, Andreas J.R., Maffia, Pasquale, Mohanta, Sarajo, Yin, Changjun   +3 more
core   +2 more sources