Results 131 to 140 of about 574,013 (307)

Sparing Organs at Risk with Simultaneous Integrated Boost Volumetric Modulated Arc Therapy for Locally Advanced Non-Small Cell Lung Cancer: An Automatic Treatment Planning Study

Cancer Management and Research, 2020
Daquan Wang,1,* Jiayun Chen,1,* Xiaodong Zhang,2 Tao Zhang,1 Luhua Wang,1 Qinfu Feng,1 Zongmei Zhou,1 Jianrong Dai,1 Nan Bi1 1Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese ...
Wang D, Chen J, Zhang X, Zhang T, Wang L, Feng Q, Zhou Z, Dai J, Bi N   +8 more
doaj  

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

CT Segmentation of Organs at Risk with Generative Adversarial Networks

, 2022
LAUREA MAGISTRALELa segmentazione di Organi a Rischio dalle Tomografie Computerizzate (TC) è un task particolarmente complicato e che richiede molto tempo da parte di radiologi specializzati.
PORTANTI, MATTIA
core  

Evaluation of Trident network against atlas and 2D U-net methods for auto-segmentation of organs at risk in nasopharyngeal carcinoma: a comparative study

Frontiers in Physics
Background and objective(s)This study evaluates the accuracy of automatic segmentation of Organs at Risk (OARs) in nasopharyngeal carcinoma (NPC) using three approaches: atlas-based, 2D U-Net, and a self-developed Trident network. Our aim was to develop,
Jinghui Pan, Jinghui Pan, Fengjiao Zhuo, Dan Li, Xiangpan Li, Qibin Song, Hao Jiang, Jinsheng Xiao, Changli Ruan   +8 more
doaj   +1 more source

Risk organizers in quest of authority : Organizing risks and risk prevention in the markets of inspection and certification

, 2011
On the basis of two empirical cases (the market of motor vehicle inspection and the market of management certification) this paper analyses different strategies used to make these markets credible and trustworthy. The market actors are referred to as risk organizers and the strategies used as risk management strategies. These risk management strategies
Tamm Hallström, Kristina, Gustafsson, Ingrid, Alexius, Susanna   +2 more
openaire   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Anatomically Consistent Segmentation of Organs at Risk in MRI with Convolutional Neural Networks

, 2019
In the revision process:Planning of radiotherapy involves accurate segmentation of a large number of organs at risk, i.e. organs for which irradiation doses should be minimized to avoid important side effects of the therapy.
Mlynarski, Pawel, Bondiau, Pierre-Yves, Delingette, Hervé, Alghamdi, Hamza, Ayache, Nicholas   +4 more
core  

Mean (± SD) of the doses for organs at risk for the 205 patients treated with volume-modulated arc therapy.

, 2015
Abbreviations: L-left; R-right PRV: planing risk volume¶: Dose received by 1% of the volume.§: Percentage volume of at least one gland which received >30 Gy radiation.*: Volume of both glands which received
Ying Sun (23237), Jun Ma (9393), Ling-Long Tang (462998), Yan-Ping Mao (432695), Guan-Qun Zhou (432692), Ai-Hua Lin (432697), Rui Guo (134395), Zhen-Yu Qi (433714), Li-Zhi Liu (432696), Meng-Zhong Liu (416667)   +9 more
core   +1 more source