Results 161 to 170 of about 76,095 (267)

Heading and Then Saccades Predict Visual Discrimination Decisions in Freely Moving Ferrets. [PDF]

eNeuro
Zhu S, Zhu T, Sharafeldin A, Mancarella M, Briggs F.   +4 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Matching-adjusted indirect comparison of tislelizumab plus lenvatinib versus sintilimab plus bevacizumab biosimilar as first-line treatment for unresectable hepatocellular carcinoma. [PDF]

Front Immunol
Wang K, Liu C, Song X, Zhao N, Zheng X.
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Tra racconto e attrazione. Forme della rappresentazione dell’Oriente nel cinema narrativo degli anni Trenta

Cinergie, 2013
Chiara Tognolotti
doaj   +1 more source

Efficacy of Adding Immune Checkpoint Inhibition to Chemotherapy, With or Without VEGF Inhibition, in Patients With Advanced <i>EGFR</i>-Mutated NSCLC: A Systematic Review and Meta-Analysis With Reconstructed Individual Patient Data. [PDF]

JTO Clin Res Rep
Di Federico A, Stumpo S, Danielli L, Corradi G, Ricciuti B, Pecci F, Alessi JV, Wang X, De Giglio A, Lo Bianco F, Mantuano F, Pantaleo MA, Sperandi F, Melotti B, Gelsomino F, Ardizzoni A.   +15 more
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Sulle tracce del sublime, nello specchio del primitivo. Note su film, spazi, alterità 1900-1930

Cinergie, 2013
Carmelo Marabello
doaj   +1 more source

Immunotherapy in advanced gastroesophageal cancers: A meta-analysis of sex-based outcomes in overall survival. [PDF]

Int J Cancer
Masetti M, Petrelli F, Pietrantonio F, Lorenzen S, Leone AG.   +4 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source