Results 231 to 240 of about 12,552 (309)

Integrative Analyses Identify a cGAS‐STING Pathway‐Driven Signature With Context‐Dependent Roles in Systemic Lupus Erythematosus

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
Zhang et al. identify M7core, a critical cGAS‐STING pathway‐driven gene signature that is activated in most lupus patients’ blood and links to lupus disease severity, lymphopenia, and lupus nephritis. They further reveal the diagnostic and pathogenic characteristics of M7core and emphasize the importance of assessing pathway activity before initiating ...
Lele Zhang   +13 more
wiley   +1 more source

Individualized Treatment in Distal and Medium Vessel Occlusion Stroke Using a Validated Explainable Counterfactual Treatment Estimation Model

open access: yesAnnals of Neurology, Volume 99, Issue 5, Page 1198-1209, May 2026.
Objective The optimal treatment for distal medium vessel occlusion (DMVO) stroke remains uncertain, and evidence comparing endovascular therapy (EVT) with medical management (MM) is limited. We aimed to develop and validate a predictive modeling tool to assess individual treatment benefit in DMVO stroke using explainable counterfactual treatment ...
Mohamed F. Doheim   +14 more
wiley   +1 more source

Some Words in Reply

open access: yes
American Anthropologist, Volume 128, Issue 2, Page 424-426, June 2026.
Andrew Brandel
wiley   +1 more source

Simultaneous Establishment of Autologous Colorectal Cancer and Mesothelial Stromal Cell Lines from Malignant Ascites Reveals a Mesothelial‐Stromal FGFR3 Axis as a Potential Vulnerability in Peritoneal Metastasis

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Colorectal cancer (CRC) with peritoneal dissemination remains a major therapeutic challenge because of poor prognosis and limited treatment options. Experimental models that accurately recapitulate tumor–mesothelial interactions are scarce. Here, we report the establishment of a novel autologous paired model comprising a CRC cell line (OMUCR‐1)
Yasuhiro Fukui   +19 more
wiley   +1 more source

Genetic Reference Gaps Limit eDNA Metabarcoding and Biodiversity Monitoring of Tropical Mangrove Ecosystems

open access: yesEnvironmental DNA, Volume 8, Issue 3, May–June 2026.
This review reveals major genetic data gaps for Philippine mangrove fauna, especially invertebrates, limiting species‐level eDNA detection. By compiling 48 years of biodiversity records and assessing reference library coverage, it highlights the need for targeted sequencing and shows how integrating eDNA with conventional surveys strengthens monitoring
Earl Kevin T. Cooper   +14 more
wiley   +1 more source

Dual‐Molten‐Salt Etching Strategy Enables Built‐in Electric Field in Mo‐MXene/NiFeSe Heterostructure for Superior OER Performance

open access: yesENERGY &ENVIRONMENTAL MATERIALS, Volume 9, Issue 3, May 2026.
A dual‐molten‐salt etching strategy was employed to construct a built‐in electric field in the Mo‐MXene/NiFeSe heterostructure to achieve excellent oxygen evolution reaction. Transition metal selenides have emerged as potential catalysts for the oxygen evolution reaction, yet their practical implementation faces two fundamental challenges: irreversible
Zuliang Zhang   +5 more
wiley   +1 more source

Targeted Therapy and Immunotherapies in Hepatocellular Carcinoma: Mechanisms and Clinical Studies

open access: yesMedComm, Volume 7, Issue 5, May 2026.
The mechanism of multiple signaling pathways and their related targeted inhibitors in HCC. (A) The mechanism of Ras/Raf/MEK/ERK signaling pathway and its related targeted inhibitors; (B) the mechanism of PI3K/AKT/mTOR signaling pathway and its crosstalk with other pathways and its related targeted inhibitors; (C) the mechanism of JAK/STAT signaling ...
Penghui He   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy