Results 101 to 110 of about 4,272,808 (305)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Better functional recovery after acute stroke in older patients managed in a new dedicated post-stroke geriatric unit compared to usual management

open access: yesThe Journal of Nutrition, Health and Aging
Objectives: A Stroke care Pathway dedicated to the ELders (SPEL) for patients with acute stroke was created in 2013 at the hospitals Pitié-Salpêtrière-Charles Foix (Paris, France).
Bruno Oquendo   +7 more
doaj   +1 more source

Assessment and Comparing the Performance of Divested Firms to Non-governmental Public Sector and Private sector in Tehran Security Exchange after the Notification of the General Policies of Article 44 [PDF]

open access: yesتحقیقات مالی اسلامی (پیوسته), 2012
This article tries to study the increase or decrease in the performance of the divested companies to the non-governmental public sector and the private sector compared to the period before the divestiture and then it tries compare the private sector and ...
Adel Azar, Ali Eslamjoo
doaj  

Oriental cholangitis

open access: yesJournal of the Belgian Society of Radiology, 2010
A 51-year-old Filipino woman was referred to our department for diagnostic and therapeutic work-up of mildly abnormal liver tests.
Maeyaert, S   +4 more
openaire   +5 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Interactions of form and orientation [PDF]

open access: yes, 1989
It is well known that the orientation of an optical pattern relative to egocentric or extraneous references affects its figural quality, that is, alters its perceived form and concomitantly delays or quickens its identification (Rock 1973).
Mittelstaedt, Horst
core   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

Oriental Philology after Orientalism

open access: yes, 2021
One can hardly imagine a more typically Orientalist discipline than philology. Its heyday in the late nineteenth century coincided with the height of colonial domination of Asia by some European nations. Thanks to the critical programme of Edward Said and those inspired by him in the late twentieth century, we now understand how Oriental philology went
openaire   +1 more source

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