Results 81 to 90 of about 4,272,808 (305)
Comparative Study of the Wisdom behind Creation of Satan from the Perspective of Allameh Tabatabaii and Fakhr al-Razi [PDF]
پژوهشهای تفسیر تطبیقی, 2018 According to the Quranic teachings, the purpose of creation is worship to God and journey in the righteous path. However, it may seem that the creation of Satan who is never set on the right path and prevents human being from achieving his destination is
mohammad ali akhavian, Ali Badpa
doaj +1 more source
Hartree-Fock Theory of Hole Stripe States
, 2001 We report on Hartree-Fock theory results for stripe states of two-dimensional hole systems in quantum wells grown on GaAs (311)A substrates. We find that the stripe orientation energy has a rich dependence on hole density, and on in-plane field magnitude
A. H. MacDonald +19 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Flood Risk Zoning Using Fuzzy Logic Model; Case Example: Lavasanat Watershed [PDF]
دانش پیشگیری و مدیریت بحرانBackground and objective Iran is prone to various natural disasters including floods. The location of zones at risks of floods is necessary for making optimal decisions for its management.
Sayad Asghari Sareskanroud +2 more
doaj
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The components of the military managment of the great prophet from the prespective of the Holy Quran and it’s implications of the contemporary world [PDF]
علوم و فنون نظامیObjective: Today, the success of institutions and organizations largely depends on the efficiency and effectiveness of management. Management models that are connected to Islamic teachings will be very effective.
ahmad dehdar +2 more
doaj +1 more source
Developing the human resource strategies with the approach to Strategic Reference Points (SRP) (Case Study: The Civil Deputy of the Isfahan Municipality) [PDF]
Problems and Perspectives in Management, 2018 Codification and implementation of human resource strategy are practiced to make a bridge between policies and human resource methods, on the one hand, and strategic goals of the organization, on the other hand.
Mahdi Shahsiahi, Amirreza Naghsh
doaj +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Frontiers in Digital HealthIntroductionHospitalised patients could benefit from the emergence of novel technologies for nursing care. There are numerous technical products available, but these rarely find their way into practice.
Ronny Klawunn +3 more
doaj +1 more source