Results 31 to 40 of about 2,652,563 (309)
Object-oriented development [PDF]
IEEE Transactions on Software Engineering, 1986 Object-oriented development is a partial-lifecycle software development method in which the decomposition of a system is based upon the concept of an object. This method is fundamentally different from traditional functional approaches to design and serves to help manage the complexity of massive software-intensive systems.
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
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Pitfalls of agent-oriented development [PDF]
Proceedings of the second international conference on Autonomous agents - AGENTS '98, 1998 While the theoretical and experimental foundations of agent-based systems are becoming increasingly well understood, comparatively little effort has been devoted to understanding the pragmatics of (multi-) agent systems development - the everyday reality of carrying out an agent-based development project.
Wooldridge, M. J., Jennings, N. R.
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Innovation and Technological Development of Industrial Regions Under Social and Economic Insecurity [PDF]
, 2015 The article is devoted to the identification of the characteristics and priorities of innovation and technological development in the industrial regions of the Russian Federation in the context of the ongoing global crisis.
Golova, I. M., Suhovey, A. F.
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Orientación a las familias de niños hiperactivos para potenciar su desarrollo individual
Humanidades Médicas, 2022 Affecting approximately 5 % of the child population, hyperactivity becomes one of the most prevalent disorders in this age group, associated with disorganization in the cognitive and behavioral sphere that manifests itself in all areas of life.
Massiel Machado Diaz, , , María Elena Luis Suazo +3 more
doaj
Obstacles in object-oriented software development [PDF]
ACM SIGPLAN Notices, 1992 Recently, a considerable number of object-oriented software development methods have been introduced to produce extensible, reusable, and robust software. We have been involved in the development of a large number of pilot applications to form our own view on object-oriented methods.
Aksit, Mehmet, Bergmans, Lodewijk
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
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Development-Oriented Tax Policy
, 2008 No public policy issue is of more importance than the structure and level of taxes. Tax reform has led governments to fall. Proposals to extend the VAT or increase its rates have been a source of political agitation in many countries, including Ecuador and Mexico.
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