Results 31 to 40 of about 2,668,543 (308)
Object-oriented development [PDF]
Object-oriented development is a partial-lifecycle software development method in which the decomposition of a system is based upon the concept of an object. This method is fundamentally different from traditional functional approaches to design and serves to help manage the complexity of massive software-intensive systems.
openaire +1 more source
Rethinking Nigeria’s Development Using African Traditional Communication Media for National Orientation [PDF]
This paper examines the problem of poor orientation of most Nigerian citizens, especially the rural dwellers, occasioned by the dearth and failure of modern media in rural Nigeria; a phenomenon that has led to a major setback in participatory governance ...
Iyorza, Stanislaus
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Pitfalls of agent-oriented development [PDF]
While the theoretical and experimental foundations of agent-based systems are becoming increasingly well understood, comparatively little effort has been devoted to understanding the pragmatics of (multi-) agent systems development - the everyday reality of carrying out an agent-based development project.
Wooldridge, M. J., Jennings, N. R.
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Selection, Orientation, and Development of the Professional Staff [PDF]
published or submitted for ...
St. John, Francis R.
core
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Orientación a las familias de niños hiperactivos para potenciar su desarrollo individual
Affecting approximately 5 % of the child population, hyperactivity becomes one of the most prevalent disorders in this age group, associated with disorganization in the cognitive and behavioral sphere that manifests itself in all areas of life.
Massiel Machado Diaz, , , María Elena Luis Suazo +3 more
doaj
Obstacles in object-oriented software development [PDF]
Recently, a considerable number of object-oriented software development methods have been introduced to produce extensible, reusable, and robust software. We have been involved in the development of a large number of pilot applications to form our own view on object-oriented methods.
Aksit, Mehmet, Bergmans, Lodewijk
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Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source

