Results 71 to 80 of about 1,139,901 (293)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

ORIENTATIONS FOR COLABORATORS

open access: yesEspaço Ameríndio, 2011
Clique no link abaixo para baixar o arquivo completo em ...
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doaj   +6 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

A Comment on Junction and Energy Conditions in Thin Shells

open access: yes, 1994
This comment contains a suggestion for a slight modification of Israel's covariant formulation of junction conditions between two spacetimes, placing both sides on equal footing with normals having uniquely defined orientations.
Barrabès C   +8 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Engaging Graduate Students in Three Easy Steps: Failures and Successes From Back-to-Back Years

open access: yesJournal of Graduate Librarianship
In Fall 2022, three librarians representing the outreach and engagement department and reference and instruction department at Loyola Marymount University's William H.
Rhonda Rosen   +2 more
doaj   +1 more source

Oriental cholangitis

open access: yesJournal of the Belgian Society of Radiology, 2010
A 51-year-old Filipino woman was referred to our department for diagnostic and therapeutic work-up of mildly abnormal liver tests.
Maeyaert, S   +4 more
openaire   +5 more sources

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

Radio and optical orientations of galaxies

open access: yes, 2009
We investigate the correlations between optical and radio isophotal position angles for 14302 SDSS galaxies with $r$ magnitudes brighter than 18 and which have been associated with extended FIRST radio sources.
Battye, R. A., Browne, I. W. A.
core   +2 more sources

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