Results 51 to 60 of about 1,139,901 (293)

Orientational analysis of atomic pair correlations in nanocrystalline indium oxide thin films

open access: yesIUCrJ
The application of grazing-incidence total X-ray scattering (GITXS) for pair distribution function (PDF) analysis using >50 keV X-rays from synchrotron light sources has created new opportunities for structural characterization of supported thin films ...
Justin M. Hoffman   +11 more
doaj   +1 more source

Improved Orientation Sampling for Indexing Diffraction Patterns of Polycrystalline Materials [PDF]

open access: yes, 2017
Orientation mapping is a widely used technique for revealing the microstructure of a polycrystalline sample. The crystalline orientation at each point in the sample is determined by analysis of the diffraction pattern, a process known as pattern indexing.
Larsen, Peter Mahler, Schmidt, Søren
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Autonomy Orientations of English Language Teachers in Turkey

open access: yesJournal of Language and Education, 2021
The present study aimed to explore autonomy orientations of English language teachers' work at an intensive language school in Turkey. The autonomy orientations of the teachers were analysed through self-determination theory.
Aslihan Bagci
doaj   +1 more source

Isotropic-nematic transition in hard-rod fluids: relation between continuous and restricted-orientation models

open access: yes, 2003
We explore models of hard-rod fluids with a finite number of allowed orientations, and construct their bulk phase diagrams within Onsager's second virial theory.
G.J. Vroege   +10 more
core   +2 more sources

Three religious orientations and five personality factors : an exploratory study among adults in England [PDF]

open access: yes, 2010
In order to explore the power of the five factor model of personality to explain individual differences recorded on measures of the three religious orientations, a sample of 198 adults in England completed established measures of the three religious ...
Clarke, Rachel   +4 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Orientations of two coupled molecules

open access: yes, 2004
Orientation states of two coupled polar molecules controlled by laser pulses are studied theoretically. By varying the period of a series of periodically applied laser pulse, transition from regular to chaotic behavior may occur. Schmidt decomposition is
Averbukh   +25 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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