Results 41 to 50 of about 1,139,901 (293)

Orientable and Negative Orientable Sequences

open access: yesDiscrete Applied Mathematics
Analogously to de Bruijn sequences, orientable sequences have application in automatic position-location applications and, until recently, studies of these sequences focused on the binary case. In recent work by Alhakim et al., a range of methods of construction were described for orientable sequences over arbitrary finite alphabets; some of these ...
Chris J. Mitchell, Peter R. Wild
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Teachers' orientations towards writing

open access: yesJournal of Writing Research, 2013
This study of 29 teachers from four states in the US investigated teachers' orientations towards writing and the influences on their beliefs. Through interviews about writing instruction, the researchers found significant differences between teachers in ...
Sarah J. McCarthey & Dumisile Mkhize
doaj  

Enumerating Cyclic Orientations of a Graph [PDF]

open access: yes, 2015
Acyclic and cyclic orientations of an undirected graph have been widely studied for their importance: an orientation is acyclic if it assigns a direction to each edge so as to obtain a directed acyclic graph (DAG) with the same vertex set; it is cyclic ...
A Itai   +11 more
core   +4 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Comparison Study of Novel Flat Evaporator Loop Heat Pipes with Different Types of Condensation Pipeline

open access: yesEnergies
Chip-level cooling has become a thermal bottleneck in next-generation data centers. Although previous studies have optimized evaporator wick structures, they are limited to a single condensation path and ignore the combined effects of the loop heat pipe (
Kangning Xiong   +3 more
doaj   +1 more source

Graphs with many strong orientations

open access: yes, 2016
We establish mild conditions under which a possibly irregular, sparse graph $G$ has "many" strong orientations. Given a graph $G$ on $n$ vertices, orient each edge in either direction with probability $1/2$ independently.
Aksoy, Sinan, Horn, Paul
core   +1 more source

The Niceness of Unique Sink Orientations [PDF]

open access: yes, 2016
Random Edge is the most natural randomized pivot rule for the simplex algorithm. Considerable progress has been made recently towards fully understanding its behavior. Back in 2001, Welzl introduced the concepts of \emph{reachmaps} and \emph{niceness} of
Gärtner, Bernd, Thomas, Antonis
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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