Results 31 to 40 of about 1,139,901 (293)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

How do orientations matter in early childhood education? Children, choices and gendering processes

Journal of Early Childhood Education Research
This paper explores children’s “own” choices in relation to gendering in ECE. Specifically, it problematizes what is often referred to as children’s “own” choices within child-centred pedagogies and emphasises how children’s choices are effects of ...
Anna Günther-Hanssen
doaj   +1 more source

Review on learning orientations [PDF]

, 2011
The need has arises towards the consideration of individual difference to let learners engage in and responsible for their own learning, retain information longer, apply the knowledge more effectively, have positive attitudes towards the subject, have ...
Abu Samah, Norazrena, Ali, Mohamad Bilal, Yahaya, Nor Affandy   +2 more
core  

Counting Planar Eulerian Orientations

, 2018
Inspired by the paper of Bonichon, Bousquet-M\'elou, Dorbec and Pennarun, we give a system of functional equations which characterise the ordinary generating function, $U(x),$ for the number of planar Eulerian orientations counted by edges.
Guttmann, Anthony J, Price, Andrew Elvey
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Formation of valuable orientations of students of pedagogical higher educational institutions during graphic activity

Освітній вимір, 2006
In article it it opened a problem of formation al students of the pedagogical higher school of vahrahle orientations by way of studying of the fine arts.
L.O. Savchenko, Yu.O. Zenkovich
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Is Choosing a Major Choosing a Career or Interesting Courses? An Investigation into College Students’ Orientations for College Majors and Their Stability

Journal of Postsecondary Student Success, 2021
Students’ orientations towards choosing their college majors lead them to make different major choices with long-term stratification implications.
Alanna Gillis, Renee Ryberg
doaj   +1 more source

Orientations for pseudoholomorphic quilts [PDF]

, 2017
We construct orientations on moduli spaces of pseudoholomorphic quilts with seam conditions in Lagrangian correspondences equipped with relative spin structures and determine the effect of various gluing operations on the orientations.
Wehrheim, Katrin, Woodward, Chris
core