Detection of Orientia sp. DNA in rodents from Asia, West Africa and Europe [PDF]
Orientia bacterium is the agent of the scrub typhus, a seriously neglected life-threatening disease in Asia. Here, we report the detection of DNA of Orientia in rodents from Europe and Africa. These findings have important implications for public health.
Jean François Cosson +10 more
doaj +7 more sources
Probable scrub typhus-like infection in Colombia: seroconversion and serological reactivity to Orientia spp. among patients with acute undifferentiated febrile illness in Villeta municipality [PDF]
Background: Scrub typhus, caused by Orientia spp., is a mite-borne disease historically restricted to the Asia-Pacific region. Autochthonous cases have been confirmed in southern Chile, while serological evidence has been reported in Peru, Honduras and ...
Carlos Ramiro Silva-Ramos +7 more
doaj +2 more sources
Evidence of Rickettsia and Orientia Infections Among Abattoir Workers in Djibouti. [PDF]
Of 49 workers at a Djiboutian abattoir, eight (16%, 95% confidence interval [CI]: 9-29) were seropositive against spotted fever group rickettsiae (SFGR), two (4%, 95% CI: 1-14) against typhus group rickettsiae, and three (6%, 95% CI: 2-17) against ...
Ahmed, Ammar Abdo +7 more
core +3 more sources
Orientia tsutsugamushi Modulates RIPK3 Cellular Levels but Does Not Inhibit Necroptosis [PDF]
Scrub typhus is an emerging chigger-borne disease caused by the obligate intracellular bacterium Orientia tsutsugamushi. Necroptosis is a form of programmed cell death (PCD) mediated by RIPK3 (serine/threonine kinase receptor interacting protein 3) and ...
Thomas E. Siff +6 more
doaj +2 more sources
Comprehensive Laboratory Analysis of a Scrub Typhus and H1N1 Influenza Co-Infection: A Case Report from Hainan, China [PDF]
Co-infection of Orientia tsutsugamushi and influenza A virus complicates diagnosis and treatment in endemic regions because of overlapping clinical features and potential synergistic inflammation.
Siqi Chen +14 more
doaj +2 more sources
Hosts and vectors of scrub typhus in Chile: epidemiological study and molecular analyses of Orientia infection in rodents and rodent-associated mites [PDF]
Candidatus Orientia chiloensis causes scrub typhus over a wide geographical range in southern Chile. The life cycle, including vectors and reservoirs of this novel rickettsial pathogen, is incompletely understood.
Constanza Martínez-Valdebenito +6 more
doaj +2 more sources
Approaches to vaccines against Orientia tsutsugamushi [PDF]
Scrub typhus is a severe mite-borne infection caused by Orientia tsutsugamushi, an obligately intracellular bacterium closely related to Rickettsia.
Gustavo eValbuena, David H Walker
doaj +2 more sources
Orientia tsutsugamushi modulates p53, the cell cycle, and genotoxicity to maintain its intracellular niche [PDF]
Infections by intracellular pathogens often cause insult to host cell DNA, which stimulates responses that ultimately eliminate the damaged cell and hence the microbial niche.
Paige E. Allen +3 more
doaj +2 more sources
Scrub typhus associated with reactive arthritis: A case report and literature review [PDF]
Scrub typhus (tsutsugamushi disease) is an acute febrile illness caused by Orientia tsutsugamushi, often found in Asia and Oceania. The presence of an eschar, characterized by a crust, is a key diagnostic finding.
Shinya Yamanaka +5 more
doaj +2 more sources
Background: Scrub typhus, an acute febrile disease caused by Orientia tsutsugamushi, is transmitted to humans through infected chigger mites. We present a case of scrub typhus in a previously healthy man from Shandong Province diagnosed using next ...
Nannan Xu +4 more
doaj +2 more sources

