Orientia tsutsugamushi ankyrin repeat-containing protein family members are Type 1 secretion system substrates that traffic to the host cell endoplasmic reticulum [PDF]
, 2015 Scrub typhus is an understudied, potentially fatal infection that threatens one billion persons in the Asia-Pacific region. How the causative obligate intracellular bacterium, Orientia tsutsugamushi, facilitates its intracellular survival and ...
Beare, Paul A. +10 more
core +3 more sources
Intracellular invasion of Orientia tsutsugamushi activates inflammasome in asc-dependent manner. [PDF]
PLoS ONE, 2012 Orientia tsutsugamushi, a causative agent of scrub typhus, is an obligate intracellular bacterium, which escapes from the endo/phagosome and replicates in the host cytoplasm. O.
Jung-Eun Koo +4 more
doaj +1 more source
A Metabolic Dependency for Host Isoprenoids in the Obligate Intracellular Pathogen Rickettsia parkeri Underlies a Sensitivity to the Statin Class of Host-Targeted Therapeutics. [PDF]
, 2019 Gram-negative bacteria in the order Rickettsiales have an obligate intracellular growth requirement, and some species cause human diseases such as typhus and spotted fever.
Ahyong, Vida +4 more
core +2 more sources
Rickettsiosis Infections in Sarawak: Epidemiological Insights and Public Health Strategies. [PDF]
Can J Infect Dis Med MicrobiolRickettsiosis infections pose a significant public health concern in Sarawak, Malaysia. Despite their importance, these infections remain poorly recognised, under‐researched and inadequately documented within the context of the Sarawak region. This comprehensive evaluation seeks to address this knowledge gap by providing an in‐depth analysis of ...
Abang RAA, Adrus M.
europepmc +2 more sources
Symbiosis in an overlooked microcosm: a systematic review of the bacterial flora of mites [PDF]
, 2015 A dataset of bacterial diversity found in mites was compiled from 193 publications (from 1964 to January 2015). A total of 143 mite species belonging to the 3 orders (Mesostigmata, Sarcoptiformes and Trombidiformes) were recorded and found to be ...
Chaisiri, Kittipong +3 more
core +2 more sources
Long-read whole genome sequencing and comparative analysis of six strains of the human pathogen Orientia tsutsugamushi. [PDF]
PLoS Neglected Tropical Diseases, 2018 BackgroundOrientia tsutsugamushi is a clinically important but neglected obligate intracellular bacterial pathogen of the Rickettsiaceae family that causes the potentially life-threatening human disease scrub typhus.
Elizabeth M Batty +11 more
doaj +1 more source
Vomocytosis: Too Much Booze, Base, or Calcium? [PDF]
, 2019 Macrophages are well known for their phagocytic activity and their role in innate immune responses. Macrophages eat non-self particles, via a variety of mechanisms, and typically break down internalized cargo into small macromolecules.
Aaron +98 more
core +2 more sources
Tropical Medicine and Infectious Disease, 2019 Scrub typhus is caused by an obligated intracellular organism, Orientia tsutsugamushi (Orientia). The disease was traditionally thought to be limited in the tsutsugamushi triangle.
Chien-Chung Chao +4 more
doaj +1 more source
Male-killing bacteria in insects: mechanisms, incidence and implications [PDF]
, 2000 Bacteria that are vertically transmitted through female hosts and kill male hosts that inherit them were first recorded in insects during the 1950s. Recent studies have shown these "male-killers" to be diverse and have led to a reappraisal of the biology
Hurst, GDD, Jiggins, FM
core +2 more sources
Clinical deterioration in community acquired infections associated with lymphocyte upsurge in immunocompetent hosts [PDF]
, 2004 Clinical deterioration during the course of community-acquired infections can occur as a result of an exaggerated immune response of the host towards the inciting pathogens, leading to immune-mediated tissue damage.
Cheng, VCC +7 more
core +1 more source