Results 171 to 180 of about 5,605 (215)

A Multi-epitope Subunit Vaccine Identification and Development Against Scrub Typhus (Orientia tsutsugamushi) Using Immunoinformatics Approaches. [PDF]

Cureus
Khichi S, Morang S, Dhamija P, Handu S.
europepmc   +1 more source

Reverse vaccinology and immunoinformatics approach to design a chimeric epitope vaccine against Orientia tsutsugamushi. [PDF]

Heliyon
Dolley A, Goswami HB, Dowerah D, Dey U, Kumar A, Hmuaka V, Mukhopadhyay R, Kundu D, Varghese GM, Doley R, Chandra Deka R, Namsa ND.   +11 more
europepmc   +1 more source

Lack of the IFN-γ signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions. [PDF]

PLoS Pathog
Liang Y, Wang H, Sun K, Sun J, Soong L.
europepmc   +1 more source

Comparative virulence analysis of seven diverse strains of Orientia tsutsugamushi reveals a multifaceted and complex interplay of virulence factors responsible for disease

Chaichana P, Satapoomin N, Kullapanich C, Chuenklin S, Mohammad A, Inthawong M, Ball EE, Burke TP, Sunyakumthorn P, Salje J.   +9 more
europepmc   +1 more source

The intracellular bacteriumOrientia tsutsugamushihijacks the adaptor protein BICD2 for dynein-based motility

Manigrasso G, Saharat K, Kullapanich C, Boulanger J, Morgan TE, Kramer H, Salje J, Carter AP.   +7 more
europepmc   +1 more source

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Scrub typhus and antibiotic-resistant Orientia tsutsugamushi

Expert Review of Anti-infective Therapy, 2021
Introduction: Scrub typhus is one of the most underdiagnosed and under-reported febrile illnesses requiring hospitalization, mainly occurring in Southeast and East Asia and the Pacific Islands, in an area referred to as the 'Tsutsugamushi Triangle.' Scrub typhus is a zoonotic rickettsial disease that is transmitted to humans by trombiculid mites.Areas ...
Chin-Te, Lu, Lih-Shinn, Wang, Po-Ren, Hsueh   +2 more
openaire   +2 more sources

Antibodies to Orientia tsutsugamushi in Thai Soldiers

The American Journal of Tropical Medicine and Hygiene, 1996
Thai soldiers who were conscripted, Royal Thai Army forces, professional Border Patrol Police, or local militia (Thai Rangers) located in any of seven provinces of Thailand were bled in April and again, four months later, in July 1989. In 1991, soldiers from five different locations in southern Thailand were bled once, in July.
C, Eamsila, P, Singsawat, A, Duangvaraporn, D, Strickman   +3 more
openaire   +2 more sources

Global gene expression profile of Orientia tsutsugamushi

PROTEOMICS, 2010
AbstractOrientia tsutsugamushi, an obligate intracellular bacterium, is the causative agent of Scrub typhus. The control mechanisms for bacterial gene expression are largely unknown. Here, the global gene expression of O. tsutsugamushi within eukaryotic cells was examined using a microarray and proteomic approaches for the first time.
Cho, BA, Cho, NH, Min, CK, Kim, SY, Yang, JS, Lee, JR, Jung, JW, Lee, WC, Kim, K, Lee, MK, Kim, S, Kim, KP, Seong, SY, Choi, MS, Kim, IS   +14 more
openaire   +3 more sources

Subversion of host cell signaling by Orientia tsutsugamushi

Microbes and Infection, 2011
Progress has been made in deciphering the mechanisms on Orientia tsutsugamushi-host interaction. The genome sequencing, microarray and proteomic analyses of this ancient bacterium have provided a wealth of new information. This paper reviews the general characteristics of O.
Yan, Ge, Yasuko, Rikihisa
openaire   +2 more sources

PREVALENCE OF RELATIVE BRADYCARDIA IN ORIENTIA TSUTSUGAMUSHI INFECTION

The American Journal of Tropical Medicine and Hygiene, 2003
We investigated 100 febrile patients infected with Orientia tsutsugamushi (the etiologic agent of scrub typhus) for the presence of relative bradycardia, defined as in increase in heart rate of < 10 beats/minutes/1°C increase in temperature. The median heart rate response for the entire febrile scrub typhus population was 9.3 beats/minute/°C and the
David M, Aronoff, George, Watt
openaire   +2 more sources