Results 91 to 100 of about 3,067,292 (342)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Iron catalysis at the origin of life
IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2017 Iron–sulphur proteins are ancient and drive fundamental processes in cells, notably electron transfer and CO2 fixation. Iron–sulphur minerals with equivalent structures could have played a key role in the origin of life. However, the ‘iron–sulphur world’
E. Camprubi +3 more
semanticscholar +1 more source
, 2010 RNA molekula sadrži genetičku informaciju i ima katalitičku ulogu, te je stoga možemo smatrati pramolekulom života. Njena uloga je vrlo bitna i u danas u biologiji.
Bratovič, Majda
core +2 more sources
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
FoodsLegumes are an interesting matrix for food production. The aim of this study was to develop functional plant-based snacks using fermented red bean (RBB) seeds enriched with the following additives: marjoram—RBM (2%); carrot—RBC (30%); and red beetroot ...
Małgorzata Gumienna +5 more
doaj +1 more source
Systems protobiology: origin of life in lipid catalytic networks
Journal of the Royal Society Interface, 2018 Life is that which replicates and evolves, but there is no consensus on how life emerged. We advocate a systems protobiology view, whereby the first replicators were assemblies of spontaneously accreting, heterogeneous and mostly non-canonical ...
D. Lancet +2 more
semanticscholar +1 more source
Review for "Life History, Mating Dynamics, and The Origin of Parental Care"
, 2021 J. Eliot B. Moss
openalex +2 more sources
Widespread abiotic methane in chromitites [PDF]
, 2018 Recurring discoveries of abiotic methane in gas seeps and springs in ophiolites and peridotite massifs worldwide raised the question of where, in which rocks, methane was generated.
Etiope, G. +8 more
core +1 more source
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source