Results 91 to 100 of about 5,461,980 (349)
A retired west-coast (U.S.A.) business man has surprised the origin of life community by announcing a major prize for origin of life research. The $50,000 award and up to $2,000,000 in potential research funding are offered “…for the best original proposal pertaining to the study of the origin of life on Earth, including an outline of work to be ...
openaire +3 more sources
A Unifying Scenario on the Origin and Evolution of Cellular and Viral Domains [PDF]
The cellular theory on the nature of life has been one of the first major advancements in biology. Viruses, however, are the most abundant life forms, and their exclusion from mainstream biology and the Tree of Life (TOL) is a major paradox in biology ...
Claudiu I. Bandea
core +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
From Protoplanets to Protolife: The Emergence and Maintenance of Life [PDF]
Despite great advances in our understanding of the formation of the Solar System, the evolution of the Earth, and the chemical basis for life, we are not much closer than the ancient Greeks to an answer of whether life has arisen and persisted on any other planet.
arxiv
Origin of life from a maker's perspective -- focus on protocellular compartments in bottom-up synthetic biology [PDF]
The origin of life is shrouded in mystery, with few surviving clues, obscured by evolutionary competition. Previous reviews have touched on the complementary approaches of top-down and bottom-up synthetic biology to augment our understanding of living systems.
arxiv
Origin and evolution of the earth and its life [PDF]
Thesis (M.A.)--Boston ...
Patch, Esther Maude
core +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
Exobiology and the origin of life [PDF]
s on planetary studies and the search for extraterrestrial life are presented. Studies of the Jovian atmosphere were conducted. An assessment of the prospects for life on Mars is presented.
Khare, B. N., Sagan, C.
core +4 more sources
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Recent Progress in Chirality Research Using Circularly Polarized Light [PDF]
(abridged) We review recent studies of chirality using circularly polarized light, along with the birth and evolution of life and planetary systems. Terrestrial life consists almost exclusively of one enantiomer, left-handed amino acids. This characteristic feature is called homochirality, whose origin is still unknown.
arxiv