Origin of Quantum Mechanical Results and Life: A Clue from Quantum Biology [PDF]
, 2018 Although quantum mechanics can accurately predict the probability distribution of outcomes in an ensemble of identical systems, it cannot predict the result of an individual system.
Dikshit, Biswaranjan
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Characteristics of synbiotics and lactobionic acid
Journal of Functional FoodsThis analysis delves into the combined advantages of synbiotics - a mix of probiotics and prebiotics, in supporting gut health and overall wellness. Synbiotics have displayed potential in enhancing function reducing inflammation and promoting digestion ...
Kamila Goderska, Peace Oluwamuyiwa Obey
doaj +1 more source
Provisioning the origin and early evolution of life
Emerging Topics in Life Sciences, 2019 There is a lot of controversy in the origin and early evolution of life field, but most people agree that at the advent of genetically coded protein synthesis, cells must have had access to ribonucleotides, amino acids, lipids and some sort of energy ...
Long-Fei Wu, J. Sutherland
semanticscholar +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Exobiology and the origin of life [PDF]
s on planetary studies and the search for extraterrestrial life are presented. Studies of the Jovian atmosphere were conducted. An assessment of the prospects for life on Mars is presented.
Khare, B. N., Sagan, C.
core +4 more sources
The Theory of Evolution is Not an Explanation for the Origin of Life [PDF]
, 2010 Justin W. Rice +4 more
openalex +1 more source
AFM Images of Viroid-Sized Rings That Self-Assemble from Mononucleotides through Wet–Dry Cycling: Implications for the Origin of Life [PDF]
, 2020 Tue Hassenkam +3 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source