Results 221 to 230 of about 2,987,022 (341)

The Genetic Code as a Chronicle of Early Events in the Origin of Life [PDF]

, 1998
Brian K. Davis
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

On the role of α-alumina in the origin of life: Surface-driven assembly of amino acids. [PDF]

Sci Adv
Wang R, Remsing RC, Klein ML, Borguet E, Carnevale V.   +4 more
europepmc   +1 more source

The hierarchical organization of autocatalytic reaction networks and its relevance to the origin of life. [PDF]

PLoS Comput Biol, 2022
Peng Z, Linderoth J, Baum DA.
europepmc   +1 more source

LIFE IS NOT MEMORY BUT ALGORITHMIC RESPONSE THE ORIGIN OF NEW ELEMENTS AND LIFE THROUGH PARTICLE–ENVIRONMENT ALGORITHMS (HSH SERIES PAPER NO. 45) [PDF]

hong seokhoun
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

On the Roles of Protein Intrinsic Disorder in the Origin of Life and Evolution. [PDF]

Life (Basel)
Uversky VN.
europepmc   +1 more source

Viroids and the Origin of Life. [PDF]

Int J Mol Sci, 2021
Moelling K, Broecker F.
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source