RNA folding studies inside peptide-rich droplets reveal roles of modified nucleosides at the origin of life. [PDF]
Sci Adv, 2023 Meyer MO +4 more
europepmc +1 more source
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
FEBS Letters, EarlyView.The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source
Directionality theory and the origin of life. [PDF]
R Soc Open SciDemetrius LA.
europepmc +1 more source
RNA enigma: "From origin of life to novel Coronavirus-COVID-19". [PDF]
Saudi J Biol Sci, 2022 Krishnaveni M, Venkatesh S.
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Oxidative stress in pediatric diseases associated with the origin of life and growth and development. [PDF]
Front Cell Dev BiolZheng B, Fu J.
europepmc +1 more source
Did Solid Surfaces Enable the Origin of Life? [PDF]
Life (Basel), 2021 Gözen İ.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Creating a foundation for origin of life outreach: How scientists relate to their field, the public, and religion. [PDF]
PLoS One, 2023 Wienand K, Kampschulte L, Heckl WM.
europepmc +1 more source