Results 81 to 90 of about 5,350,711 (346)
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
FoodsLegumes are an interesting matrix for food production. The aim of this study was to develop functional plant-based snacks using fermented red bean (RBB) seeds enriched with the following additives: marjoram—RBM (2%); carrot—RBC (30%); and red beetroot ...
Małgorzata Gumienna +5 more
doaj +1 more source
A Unifying Scenario on the Origin and Evolution of Cellular and Viral Domains [PDF]
, 2009 The cellular theory on the nature of life has been one of the first major advancements in biology. Viruses, however, are the most abundant life forms, and their exclusion from mainstream biology and the Tree of Life (TOL) is a major paradox in biology ...
Claudiu I. Bandea
core +1 more source
From Cosmos to Intelligent Life: The Four Ages of Astrobiology [PDF]
, 2012 The history of life on Earth and in other potential life-bearing planetary platforms is deeply linked to the history of the universe. Since life as we know it relies on chemical elements forged in dying heavy stars, the universe needs to be old enough for stars to form and evolve. Current cosmological theory indicates that the universe is 13.7$\pm 0.13$
arxiv +1 more source
Effective Metagraph-based Life Pattern Clustering with Big Human Mobility Data [PDF]
arXiv, 2021 Life pattern clustering is essential for abstracting the groups' characteristics of daily mobility patterns and activity regularity. Based on millions of GPS records, this paper proposed a framework on the life pattern clustering which can efficiently identify the groups have similar life pattern.
arxiv
FEBS Letters, EarlyView.Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard +7 more
wiley +1 more source
Origin and evolution of the earth and its life [PDF]
, 1921 Thesis (M.A.)--Boston ...
Patch, Esther Maude
core +1 more source
The Origin of Chiral Life [PDF]
arXiv, 2020 The phenomenon of life is discussed within a framework of its origin as defined by four hypotheses. The 1. hypothesis says: Life, as we know, is (H-C-N-O) based and relies on the number of bulk (Na-Mg-P-S-Cl-K-Ca) and trace elements (Cr-Mn-Fe-Co-Ni-Cu-Zn-Se-Mo-I-W, and possibly Li-B-F-Si-V-As).
arxiv